Reconstruction de l'oesophage cervical par transplant libre d'anse jéjunale. Etude expérimentale chez le chien.

Translated title of the contribution: Reconstruction of the cervical esophagus by the free transfer of a jejunal loop. An experimental study in dogs

T. A. Mustoe, Marvin P. Fried, Z. Horowitz, L. E. Botnick, M. Strome

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A study was performed in twenty dogs in order to evaluate the chronic effects of free jejunal transfer and possible subsequent radiation therapy. Ten dogs were sacrificed within one week after surgery, three survived twelve to twenty days, and seven survived longer than six weeks with only one completing a full course of radiation equivalent to 6,000 rads to the jejunal flap. Fistulization was the most frequent complication in short-term and intermediate survivors. Inanition due to a functional rather than anatomic stenosis and dysmotility was observed in the long-term survivors. Interval oesophagoscopy and biopsy was of no additional value in evaluating flap survival. The jejunum of the animal receiving radiation showed a greater submucosal inflammatory response when compared to the other animals. Attempts at intraoperative cooling of the jejunal segment did not increase bowel survival or diminish the rate of fistulization.

Original languageFrench
Pages (from-to)227-233
Number of pages7
JournalAnnales d"oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d"oto-laryngologie des hopitaux de Paris
Volume103
Issue number4
StatePublished - 1986
Externally publishedYes

Fingerprint

Esophagus
Survivors
Dogs
Radiation
Esophagoscopy
Survival
Jejunum
Pathologic Constriction
Radiotherapy
Biopsy

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

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title = "Reconstruction de l'oesophage cervical par transplant libre d'anse j{\'e}junale. Etude exp{\'e}rimentale chez le chien.",
abstract = "A study was performed in twenty dogs in order to evaluate the chronic effects of free jejunal transfer and possible subsequent radiation therapy. Ten dogs were sacrificed within one week after surgery, three survived twelve to twenty days, and seven survived longer than six weeks with only one completing a full course of radiation equivalent to 6,000 rads to the jejunal flap. Fistulization was the most frequent complication in short-term and intermediate survivors. Inanition due to a functional rather than anatomic stenosis and dysmotility was observed in the long-term survivors. Interval oesophagoscopy and biopsy was of no additional value in evaluating flap survival. The jejunum of the animal receiving radiation showed a greater submucosal inflammatory response when compared to the other animals. Attempts at intraoperative cooling of the jejunal segment did not increase bowel survival or diminish the rate of fistulization.",
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T1 - Reconstruction de l'oesophage cervical par transplant libre d'anse jéjunale. Etude expérimentale chez le chien.

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AU - Fried, Marvin P.

AU - Horowitz, Z.

AU - Botnick, L. E.

AU - Strome, M.

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AB - A study was performed in twenty dogs in order to evaluate the chronic effects of free jejunal transfer and possible subsequent radiation therapy. Ten dogs were sacrificed within one week after surgery, three survived twelve to twenty days, and seven survived longer than six weeks with only one completing a full course of radiation equivalent to 6,000 rads to the jejunal flap. Fistulization was the most frequent complication in short-term and intermediate survivors. Inanition due to a functional rather than anatomic stenosis and dysmotility was observed in the long-term survivors. Interval oesophagoscopy and biopsy was of no additional value in evaluating flap survival. The jejunum of the animal receiving radiation showed a greater submucosal inflammatory response when compared to the other animals. Attempts at intraoperative cooling of the jejunal segment did not increase bowel survival or diminish the rate of fistulization.

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