Abstract
The evolution of a selectively neutral modifier of recombination is studied under different conditions of selection on the major genes. In a finite population a simulation study is carried out in which the phenotype is computed additively from the genotype at twenty genes. The fitness is taken to be a function of the phenotype and we show that when this function is very jagged, low recombination has a strong advantage. When the function is smooth and of the disruptive-selection kind, high recombination may be favored in both finite and very large populations. In a deterministic numerical study of disruptive selection on two loci it is shown that the evolution of recombination depends on the initial frequencies at the selected loci, on the exact shape of selection and on the strength of the selection. In general, when the selection is disruptive and very strong, it is possible to find conditions under which higher recombination will be favored.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 57-67 |
| Number of pages | 11 |
| Journal | Physica D: Nonlinear Phenomena |
| Volume | 56 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1992 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Applied Mathematics
- Statistical and Nonlinear Physics
Cite this
Recombination dynamics and the fitness landscape. / Bergman, Aviv; Feldman, Marcus W.
In: Physica D: Nonlinear Phenomena, Vol. 56, No. 1, 1992, p. 57-67.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Recombination dynamics and the fitness landscape
AU - Bergman, Aviv
AU - Feldman, Marcus W.
PY - 1992
Y1 - 1992
N2 - The evolution of a selectively neutral modifier of recombination is studied under different conditions of selection on the major genes. In a finite population a simulation study is carried out in which the phenotype is computed additively from the genotype at twenty genes. The fitness is taken to be a function of the phenotype and we show that when this function is very jagged, low recombination has a strong advantage. When the function is smooth and of the disruptive-selection kind, high recombination may be favored in both finite and very large populations. In a deterministic numerical study of disruptive selection on two loci it is shown that the evolution of recombination depends on the initial frequencies at the selected loci, on the exact shape of selection and on the strength of the selection. In general, when the selection is disruptive and very strong, it is possible to find conditions under which higher recombination will be favored.
AB - The evolution of a selectively neutral modifier of recombination is studied under different conditions of selection on the major genes. In a finite population a simulation study is carried out in which the phenotype is computed additively from the genotype at twenty genes. The fitness is taken to be a function of the phenotype and we show that when this function is very jagged, low recombination has a strong advantage. When the function is smooth and of the disruptive-selection kind, high recombination may be favored in both finite and very large populations. In a deterministic numerical study of disruptive selection on two loci it is shown that the evolution of recombination depends on the initial frequencies at the selected loci, on the exact shape of selection and on the strength of the selection. In general, when the selection is disruptive and very strong, it is possible to find conditions under which higher recombination will be favored.
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UR - http://www.scopus.com/inward/citedby.url?scp=0001852793&partnerID=8YFLogxK
U2 - 10.1016/0167-2789(92)90050-W
DO - 10.1016/0167-2789(92)90050-W
M3 - Article
VL - 56
SP - 57
EP - 67
JO - Physica D: Nonlinear Phenomena
JF - Physica D: Nonlinear Phenomena
SN - 0167-2789
IS - 1
ER -