Recognition of upper airway and surrounding structures at MRI in pediatric PCOS and OSAS

Yubing Tong, J. K. Udupa, D. Odhner, Sanghun Sin, Raanan Arens

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

Obstructive Sleep Apnea Syndrome (OSAS) is common in obese children with risk being 4.5 fold compared to normal control subjects. Polycystic Ovary Syndrome (PCOS) has recently been shown to be associated with OSAS that may further lead to significant cardiovascular and neuro-cognitive deficits. We are investigating image-based biomarkers to understand the architectural and dynamic changes in the upper airway and the surrounding hard and soft tissue structures via MRI in obese teenage children to study OSAS. At the previous SPIE conferences, we presented methods underlying Fuzzy Object Models (FOMs) for Automatic Anatomy Recognition (AAR) based on CT images of the thorax and the abdomen. The purpose of this paper is to demonstrate that the AAR approach is applicable to a different body region and image modality combination, namely in the study of upper airway structures via MRI. FOMs were built hierarchically, the smaller sub-objects forming the offspring of larger parent objects. FOMs encode the uncertainty and variability present in the form and relationships among the objects over a study population. Totally 11 basic objects (17 including composite) were modeled. Automatic recognition for the best pose of FOMs in a given image was implemented by using four methods - a one-shot method that does not require search, another three searching methods that include Fisher Linear Discriminate (FLD), a b-scale energy optimization strategy, and optimum threshold recognition method. In all, 30 multi-fold cross validation experiments based on 15 patient MRI data sets were carried out to assess the accuracy of recognition. The results indicate that the objects can be recognized with an average location error of less than 5 mm or 2-3 voxels. Then the iterative relative fuzzy connectedness (IRFC) algorithm was adopted for delineation of the target organs based on the recognized results. The delineation results showed an overall FP and TP volume fraction of 0.02 and 0.93.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
Volume8670
DOIs
StatePublished - 2013
EventMedical Imaging 2013: Computer-Aided Diagnosis - Lake Buena Vista, FL, United States
Duration: Feb 12 2013Feb 14 2013

Other

OtherMedical Imaging 2013: Computer-Aided Diagnosis
CountryUnited States
CityLake Buena Vista, FL
Period2/12/132/14/13

Fingerprint

sleep
ovaries
Ovary
Pediatrics
Sleep
respiration
Magnetic resonance imaging
Object Model
Fuzzy Model
delineation
anatomy
Anatomy
Fold
Energy Optimization
Biomarkers
thorax
abdomen
CT Image
Soft Tissue
biomarkers

Keywords

  • Fuzzy connectedness
  • Fuzzy models
  • Object recognition
  • Obstructive sleep apnea
  • Segmentation

ASJC Scopus subject areas

  • Applied Mathematics
  • Computer Science Applications
  • Electrical and Electronic Engineering
  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

Cite this

Tong, Y., Udupa, J. K., Odhner, D., Sin, S., & Arens, R. (2013). Recognition of upper airway and surrounding structures at MRI in pediatric PCOS and OSAS. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 8670). [86702S] https://doi.org/10.1117/12.2007948

Recognition of upper airway and surrounding structures at MRI in pediatric PCOS and OSAS. / Tong, Yubing; Udupa, J. K.; Odhner, D.; Sin, Sanghun; Arens, Raanan.

Proceedings of SPIE - The International Society for Optical Engineering. Vol. 8670 2013. 86702S.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tong, Y, Udupa, JK, Odhner, D, Sin, S & Arens, R 2013, Recognition of upper airway and surrounding structures at MRI in pediatric PCOS and OSAS. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 8670, 86702S, Medical Imaging 2013: Computer-Aided Diagnosis, Lake Buena Vista, FL, United States, 2/12/13. https://doi.org/10.1117/12.2007948
Tong Y, Udupa JK, Odhner D, Sin S, Arens R. Recognition of upper airway and surrounding structures at MRI in pediatric PCOS and OSAS. In Proceedings of SPIE - The International Society for Optical Engineering. Vol. 8670. 2013. 86702S https://doi.org/10.1117/12.2007948
Tong, Yubing ; Udupa, J. K. ; Odhner, D. ; Sin, Sanghun ; Arens, Raanan. / Recognition of upper airway and surrounding structures at MRI in pediatric PCOS and OSAS. Proceedings of SPIE - The International Society for Optical Engineering. Vol. 8670 2013.
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