Abstract
Discovered serendipitously in the course of studies on the mechanism of glucagon stimulation of hepatic cyclic AMP formation, G-proteins have emerged as an expanding family of signal transducers, coupling diverse receptors and effectors. Quantitative and/or qualitative changes in G-proteins may profoundly affect hormone action, and can lead to clinically apparent endocrine dysfunction.
Original language | English (US) |
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Pages (from-to) | 72-76 |
Number of pages | 5 |
Journal | Trends in Endocrinology and Metabolism |
Volume | 1 |
Issue number | 2 |
DOIs | |
State | Published - 1989 |
Externally published | Yes |
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Endocrinology