Real-Time Thermoacoustic Imaging and Thermometry during Focused Microwave Heating in Multilayer Breast Phantom

Chandra Karunakaran, Srishti Saraswat, Jinpil Tak, Hongbo Zhao, Hao Xin, Russell S. Witte

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This study describes real-time thermoacoustic imaging (TAI) and thermometry (TAT) for feedback during thermal therapies. The system uses a linear ultrasound array and imaging system to noninvasively estimate temperature. The system was validated in gel phantoms, muscle and fat tissue samples. A mean error between 10 and 20% per degree was observed for estimating temperature. A TAT system using a single element ultrasound probe was also integrated with a focused microwave therapy (FMT) setup for generating local heating, leading to a mean error of 1.18±0.87 °C compared to thermocouples placed near the region of interest. The results support the long-term goal of developing a closed-loop platform for image-guided ablation therapy for breast cancer.

Original languageEnglish (US)
Title of host publication2019 IEEE International Ultrasonics Symposium, IUS 2019
PublisherIEEE Computer Society
Pages536-539
Number of pages4
ISBN (Electronic)9781728145969
DOIs
StatePublished - Oct 2019
Event2019 IEEE International Ultrasonics Symposium, IUS 2019 - Glasgow, United Kingdom
Duration: Oct 6 2019Oct 9 2019

Publication series

NameIEEE International Ultrasonics Symposium, IUS
Volume2019-October
ISSN (Print)1948-5719
ISSN (Electronic)1948-5727

Conference

Conference2019 IEEE International Ultrasonics Symposium, IUS 2019
CountryUnited Kingdom
CityGlasgow
Period10/6/1910/9/19

Fingerprint

breast
temperature measurement
therapy
microwaves
heating
fats
linear arrays
thermocouples
muscles
ablation
estimating
platforms
cancer
gels
temperature
probes
estimates

Keywords

  • breast cancer
  • focused microwave therapy
  • hyperthermia
  • radiofrequency ablation

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Karunakaran, C., Saraswat, S., Tak, J., Zhao, H., Xin, H., & Witte, R. S. (2019). Real-Time Thermoacoustic Imaging and Thermometry during Focused Microwave Heating in Multilayer Breast Phantom. In 2019 IEEE International Ultrasonics Symposium, IUS 2019 (pp. 536-539). [8925833] (IEEE International Ultrasonics Symposium, IUS; Vol. 2019-October). IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2019.8925833

Real-Time Thermoacoustic Imaging and Thermometry during Focused Microwave Heating in Multilayer Breast Phantom. / Karunakaran, Chandra; Saraswat, Srishti; Tak, Jinpil; Zhao, Hongbo; Xin, Hao; Witte, Russell S.

2019 IEEE International Ultrasonics Symposium, IUS 2019. IEEE Computer Society, 2019. p. 536-539 8925833 (IEEE International Ultrasonics Symposium, IUS; Vol. 2019-October).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Karunakaran, C, Saraswat, S, Tak, J, Zhao, H, Xin, H & Witte, RS 2019, Real-Time Thermoacoustic Imaging and Thermometry during Focused Microwave Heating in Multilayer Breast Phantom. in 2019 IEEE International Ultrasonics Symposium, IUS 2019., 8925833, IEEE International Ultrasonics Symposium, IUS, vol. 2019-October, IEEE Computer Society, pp. 536-539, 2019 IEEE International Ultrasonics Symposium, IUS 2019, Glasgow, United Kingdom, 10/6/19. https://doi.org/10.1109/ULTSYM.2019.8925833
Karunakaran C, Saraswat S, Tak J, Zhao H, Xin H, Witte RS. Real-Time Thermoacoustic Imaging and Thermometry during Focused Microwave Heating in Multilayer Breast Phantom. In 2019 IEEE International Ultrasonics Symposium, IUS 2019. IEEE Computer Society. 2019. p. 536-539. 8925833. (IEEE International Ultrasonics Symposium, IUS). https://doi.org/10.1109/ULTSYM.2019.8925833
Karunakaran, Chandra ; Saraswat, Srishti ; Tak, Jinpil ; Zhao, Hongbo ; Xin, Hao ; Witte, Russell S. / Real-Time Thermoacoustic Imaging and Thermometry during Focused Microwave Heating in Multilayer Breast Phantom. 2019 IEEE International Ultrasonics Symposium, IUS 2019. IEEE Computer Society, 2019. pp. 536-539 (IEEE International Ultrasonics Symposium, IUS).
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