Rationale for growth hormone therapy in children with chronic kidney disease

Larry A. Greenbaum; Marcela Del Rio; Fatai Bamgbola; Frederick Kaskel

doi:10.1053/j.ackd.2004.07.005

Rationale for growth hormone therapy in children with chronic kidney disease

Larry A. Greenbaum, Marcela Del Rio, Fatai Bamgbola, Frederick Kaskel

Pediatrics

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Growth retardation is a common complication in children with chronic kidney disease. Treatable causes of growth retardation in these patients include renal osteodystrophy, metabolic acidosis, and inadequate nutritional intake. In addition, disturbances in the growth hormone-insulinlike growth factor I axis are a major cause of decreased growth. Administration of recombinant human growth hormone can overcome this problem, allowing catch-up growth and achievement of normal or improved adult height.

Original language	English (US)
Pages (from-to)	377-386
Number of pages	10
Journal	Advances in Chronic Kidney Disease
Volume	11
Issue number	4
DOIs	https://doi.org/10.1053/j.ackd.2004.07.005
State	Published - Oct 2004

Keywords

Chronic kidney disease
IGF-I
growth failure
recombinant human growth hormone

ASJC Scopus subject areas

Nephrology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1053/j.ackd.2004.07.005

Cite this

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title = "Rationale for growth hormone therapy in children with chronic kidney disease",

abstract = "Growth retardation is a common complication in children with chronic kidney disease. Treatable causes of growth retardation in these patients include renal osteodystrophy, metabolic acidosis, and inadequate nutritional intake. In addition, disturbances in the growth hormone-insulinlike growth factor I axis are a major cause of decreased growth. Administration of recombinant human growth hormone can overcome this problem, allowing catch-up growth and achievement of normal or improved adult height.",

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AU - Greenbaum, Larry A.

AU - Del Rio, Marcela

AU - Bamgbola, Fatai

AU - Kaskel, Frederick

PY - 2004/10

Y1 - 2004/10

N2 - Growth retardation is a common complication in children with chronic kidney disease. Treatable causes of growth retardation in these patients include renal osteodystrophy, metabolic acidosis, and inadequate nutritional intake. In addition, disturbances in the growth hormone-insulinlike growth factor I axis are a major cause of decreased growth. Administration of recombinant human growth hormone can overcome this problem, allowing catch-up growth and achievement of normal or improved adult height.

AB - Growth retardation is a common complication in children with chronic kidney disease. Treatable causes of growth retardation in these patients include renal osteodystrophy, metabolic acidosis, and inadequate nutritional intake. In addition, disturbances in the growth hormone-insulinlike growth factor I axis are a major cause of decreased growth. Administration of recombinant human growth hormone can overcome this problem, allowing catch-up growth and achievement of normal or improved adult height.

KW - Chronic kidney disease

KW - IGF-I

KW - growth failure

KW - recombinant human growth hormone

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Rationale for growth hormone therapy in children with chronic kidney disease

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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