Rapid Neurological Recovery Following Partial Surgical Resection of Spinal Glioblastoma Multiforme in a Pediatric Patient Presenting with Complete Paraplegia

Gabriel N. Friedman, Benjamin L. Grannan, Vijay Yanamadala, Ganesh M. Shankar, John C. Dewitt, Vidya Puthenpura, Robert M. Koffie, Shannon M. Macdonald, David H. Ebb, Matthew P. Frosch, Ann Christine Duhaime

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Pediatric spinal cord glioblastoma multiforme is a rare entity with a poor prognosis often presenting with lower extremity weakness or paralysis. Previous literature suggests that aggressive surgical resection may provide overall survival benefit; however, there is limited concurrent analysis demonstrating neurological recovery following surgical resection. We report the case of a 9-year-old boy who presented with complete paraplegia and regained the ability to ambulate independently following subtotal surgical resection, radiation, and chemotherapy. The case demonstrates the balance between meaningful neurological recovery and overall survival when deciding on the extent of resection in cases of pediatric spinal glioblastoma multiforme.

Original languageEnglish (US)
Pages (from-to)e286-e290
JournalJournal of Pediatric Hematology/Oncology
Volume38
Issue number8
DOIs
StatePublished - Nov 1 2016
Externally publishedYes

Keywords

  • glioblastoma multiforme
  • oncology
  • pediatric
  • spinal

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

Fingerprint Dive into the research topics of 'Rapid Neurological Recovery Following Partial Surgical Resection of Spinal Glioblastoma Multiforme in a Pediatric Patient Presenting with Complete Paraplegia'. Together they form a unique fingerprint.

Cite this