Raman difference studies of protein-nucleic acid interactions

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Raman difference spectroscopy combined with isotope editing procedures were employed to obtain the Raman spectra of phosphates, nucleotides, nucleic acids and their fragments when bound to several proteins. The vibrational spectra were analyzed using a variety of empirical and ab initio methods to relate the vibrational wavenumbers to hydrogen bonding strengths, bond orders, bond lengths and geometry and to establish how the proteins bring about these interactions. Some recent results obtained using these methods are reviewed.

Original languageEnglish (US)
Pages (from-to)685-691
Number of pages7
JournalJournal of Raman Spectroscopy
Volume30
Issue number8
StatePublished - 1999

Fingerprint

Nucleic acids
Nucleic Acids
Proteins
Bond length
Vibrational spectra
Nucleotides
Isotopes
Raman scattering
Hydrogen bonds
Phosphates
Spectroscopy
Geometry

ASJC Scopus subject areas

  • Spectroscopy

Cite this

Raman difference studies of protein-nucleic acid interactions. / Deng, Hua; Callender, Robert.

In: Journal of Raman Spectroscopy, Vol. 30, No. 8, 1999, p. 685-691.

Research output: Contribution to journalArticle

@article{5bb0699646254c58a3cd64053f750673,
title = "Raman difference studies of protein-nucleic acid interactions",
abstract = "Raman difference spectroscopy combined with isotope editing procedures were employed to obtain the Raman spectra of phosphates, nucleotides, nucleic acids and their fragments when bound to several proteins. The vibrational spectra were analyzed using a variety of empirical and ab initio methods to relate the vibrational wavenumbers to hydrogen bonding strengths, bond orders, bond lengths and geometry and to establish how the proteins bring about these interactions. Some recent results obtained using these methods are reviewed.",
author = "Hua Deng and Robert Callender",
year = "1999",
language = "English (US)",
volume = "30",
pages = "685--691",
journal = "Journal of Raman Spectroscopy",
issn = "0377-0486",
publisher = "John Wiley and Sons Ltd",
number = "8",

}

TY - JOUR

T1 - Raman difference studies of protein-nucleic acid interactions

AU - Deng, Hua

AU - Callender, Robert

PY - 1999

Y1 - 1999

N2 - Raman difference spectroscopy combined with isotope editing procedures were employed to obtain the Raman spectra of phosphates, nucleotides, nucleic acids and their fragments when bound to several proteins. The vibrational spectra were analyzed using a variety of empirical and ab initio methods to relate the vibrational wavenumbers to hydrogen bonding strengths, bond orders, bond lengths and geometry and to establish how the proteins bring about these interactions. Some recent results obtained using these methods are reviewed.

AB - Raman difference spectroscopy combined with isotope editing procedures were employed to obtain the Raman spectra of phosphates, nucleotides, nucleic acids and their fragments when bound to several proteins. The vibrational spectra were analyzed using a variety of empirical and ab initio methods to relate the vibrational wavenumbers to hydrogen bonding strengths, bond orders, bond lengths and geometry and to establish how the proteins bring about these interactions. Some recent results obtained using these methods are reviewed.

UR - http://www.scopus.com/inward/record.url?scp=19844369236&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=19844369236&partnerID=8YFLogxK

M3 - Article

VL - 30

SP - 685

EP - 691

JO - Journal of Raman Spectroscopy

JF - Journal of Raman Spectroscopy

SN - 0377-0486

IS - 8

ER -