Abstract
Radionuclide imaging studies are routinely used to evaluate patients suspected of having musculoskeletal infection. Three-phase bone imaging is readily available, relatively inexpensive, and very accurate in the setting of otherwise normal bone. Labeled leukocyte imaging should be used in cases of "complicating osteomyelitis" such as prosthetic joint infection. This test also is useful in clinically unsuspected diabetic pedal osteomyelitis as well as in the neuropathic joint. It is often necessary, however, to perform complementary bone marrow imaging, to maximize the accuracy of labeled leukocyte imaging. In contrast to other regions in the skeleton, labeled leukocyte imaging is not useful for diagnosing spinal osteomyelitis. At the moment, gallium is the preferred radionuclide procedure for this condition and is a useful adjunct to magnetic resonance imaging. FDG-PET likely will play an important role in the evaluation of musculoskeletal infection, especially spinal osteomyelitis, and may replace gallium imaging for this purpose.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 15-27 |
| Number of pages | 13 |
| Journal | Brazilian Archives of Biology and Technology |
| Volume | 50 |
| Issue number | SPECIALISSUE |
| DOIs | |
| State | Published - 2007 |
| Externally published | Yes |
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Keywords
- Bone scintigraphy
- FDG-PET
- Gallium
- Labeled leukocytes
- Musculoskeletal infection
- Osteomyelitis
ASJC Scopus subject areas
- General
Cite this
Radionuclide imaging of musculoskeletal infection. / Palestro, Christopher J.; Love, Charito.
In: Brazilian Archives of Biology and Technology, Vol. 50, No. SPECIALISSUE, 2007, p. 15-27.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Radionuclide imaging of musculoskeletal infection
AU - Palestro, Christopher J.
AU - Love, Charito
PY - 2007
Y1 - 2007
N2 - Radionuclide imaging studies are routinely used to evaluate patients suspected of having musculoskeletal infection. Three-phase bone imaging is readily available, relatively inexpensive, and very accurate in the setting of otherwise normal bone. Labeled leukocyte imaging should be used in cases of "complicating osteomyelitis" such as prosthetic joint infection. This test also is useful in clinically unsuspected diabetic pedal osteomyelitis as well as in the neuropathic joint. It is often necessary, however, to perform complementary bone marrow imaging, to maximize the accuracy of labeled leukocyte imaging. In contrast to other regions in the skeleton, labeled leukocyte imaging is not useful for diagnosing spinal osteomyelitis. At the moment, gallium is the preferred radionuclide procedure for this condition and is a useful adjunct to magnetic resonance imaging. FDG-PET likely will play an important role in the evaluation of musculoskeletal infection, especially spinal osteomyelitis, and may replace gallium imaging for this purpose.
AB - Radionuclide imaging studies are routinely used to evaluate patients suspected of having musculoskeletal infection. Three-phase bone imaging is readily available, relatively inexpensive, and very accurate in the setting of otherwise normal bone. Labeled leukocyte imaging should be used in cases of "complicating osteomyelitis" such as prosthetic joint infection. This test also is useful in clinically unsuspected diabetic pedal osteomyelitis as well as in the neuropathic joint. It is often necessary, however, to perform complementary bone marrow imaging, to maximize the accuracy of labeled leukocyte imaging. In contrast to other regions in the skeleton, labeled leukocyte imaging is not useful for diagnosing spinal osteomyelitis. At the moment, gallium is the preferred radionuclide procedure for this condition and is a useful adjunct to magnetic resonance imaging. FDG-PET likely will play an important role in the evaluation of musculoskeletal infection, especially spinal osteomyelitis, and may replace gallium imaging for this purpose.
KW - Bone scintigraphy
KW - FDG-PET
KW - Gallium
KW - Labeled leukocytes
KW - Musculoskeletal infection
KW - Osteomyelitis
UR - http://www.scopus.com/inward/record.url?scp=70449519580&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70449519580&partnerID=8YFLogxK
U2 - 10.1590/S1516-89132007000600003
DO - 10.1590/S1516-89132007000600003
M3 - Article
VL - 50
SP - 15
EP - 27
JO - Brazilian Archives of Biology and Technology
JF - Brazilian Archives of Biology and Technology
SN - 1516-8913
IS - SPECIALISSUE
ER -