Radioactive excretion in human milk following administration of technetium Tc 99m macroaggregated albumin

W. B. Pittard, Irwin R. Merkatz, B. D. Fletcher

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Albumin-tagged sodium pertechnetate (technetium) is routinely used in nuclear medicine for scanning procedures of the lung. The rate of excretion of this radionuclide into breast milk and the resultant potential radiation hazard to the nursing infant have received little attention. Therefore the milk from a nursing mother who required a lung scan because of suspected pulmonary emboli using an intravenous injection of 4 mCi of technetium Tc 99m macroaggregated human serum albumin was monitored. Albumin tagging severely limited the entrance of technetium into her milk and the radioactivity of the milk returned to base line by 24 hours. A total of 2.02 μCi of technetium was measured in the 24-hour milk collection after technetium injection and 94% of this amount was excreted by 15.5 hours. This amount of technetium administered orally to a newborn would deliver a total body radiation dose of .3 mrad. Therefore, an infant would receive trivial doses of radiation if breast-feeding were resumed 15.5 hours after administration of the radionuclide to the mother and nursing can clearly be resumed safely 24 hours after injection.

Original languageEnglish (US)
Pages (from-to)231-234
Number of pages4
JournalPediatrics
Volume70
Issue number2
StatePublished - 1982
Externally publishedYes

Fingerprint

Technetium Tc 99m Aggregated Albumin
Technetium
Human Milk
Milk
Sodium Pertechnetate Tc 99m
Nursing
Radiation
Radioisotopes
Lung
Albumins
Mothers
Injections
Nuclear Medicine
Breast Feeding
Embolism
Serum Albumin
Intravenous Injections
Radioactivity
Newborn Infant

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Radioactive excretion in human milk following administration of technetium Tc 99m macroaggregated albumin. / Pittard, W. B.; Merkatz, Irwin R.; Fletcher, B. D.

In: Pediatrics, Vol. 70, No. 2, 1982, p. 231-234.

Research output: Contribution to journalArticle

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