TY - JOUR
T1 - RACE-ETHNIC DIFFERENCES OF ST-ELEVATION MYOCARDIAL INFARCTION
T2 - FINDINGS FROM A NEW YORK HEALTH SYSTEM REGISTRY
AU - Murray, Christopher S.G.
AU - Zamora, Cristian
AU - Shitole, Sanyog G.
AU - Christa, Panagiota
AU - Lee, Un Jung
AU - Bortnick, Anna E.
AU - Kizer, Jorge
AU - Rodriguez, Carlos J.
N1 - Funding Information:
The Einstein-Rockefeller-CUNY Center for AIDS Research (P30-AI124414) is supported by the following NIH Co-Funding and Participating Institutes and Centers: NIAID, NCI, NICHD, NHLBI, NIDA, NIMH, NIA, FIC and OAR. American Heart Association, Grant/Award Number: 17MCPRP33630098; Montefiore Department of Medicine, Division of Cardiology; National Institutes of Health, Grant/Award Numbers: K23HL146982, K24 HL135493.
Publisher Copyright:
© 2022 Ethnicity and Disease, Inc.. All rights reserved.
PY - 2022/6
Y1 - 2022/6
N2 - Background: Race and ethnicity are major considerations in the incidence, management, and long-term outcome of ST-elevation myocardial infarction (STEMI) in the United States, but there is limited existing comparative data. Methods: We assembled a registry in a health system serving Bronx, NY of STEMI patients from 2008-2014 and analyzed differences in presentation, treatment and mortality between Hispanic/Latino (H/L), non-Hispanic Black (NHB) and non-Hispanic White (NHW). Upon discharge post-treatment for STEMI, all patients were followed for a median of 4.4 years (interquartile range 2.5, 6.0). Out of 966 STEMI patients, mean age was 61 years, 46% were H/L and 65% were male. H/Ls and NHBs had a higher prevalence of hypertension and diabetes mellitus than their NHW counterparts, coinciding with a lower socioeconomic status (SES). Results: The number of critically diseased vessels found at cardiac catheterization and mean troponin levels did not vary by race-ethnicity; neither did the adjusted hazard ratios (HR) for death. However, age-sex adjusted rates of general hospital readmission were higher in NHBs vs NHWs (HR 1.30, P=.03). Age-sex adjusted cardiovascular readmissions rates were higher in H/Ls than NHWs (HR 1.42, P=.03). Age-sex adjusted heart failure readmissions were increased for both H/Ls (HR 2.14, P=.01) and NHBs (HR 2.12, P=.02) over NHWs. Conclusions: Among STEMI patients, a higher prevalence of modifiable cardiovascular risk factors and a lower SES was seen among NHBs and H/Ls compared to NHWs. Despite similar coronary disease severity and in-hospital death, NHBs and H/Ls had a greater risk of general, cardiovascular and heart failure readmissions post-STEMI compared to NHWs.
AB - Background: Race and ethnicity are major considerations in the incidence, management, and long-term outcome of ST-elevation myocardial infarction (STEMI) in the United States, but there is limited existing comparative data. Methods: We assembled a registry in a health system serving Bronx, NY of STEMI patients from 2008-2014 and analyzed differences in presentation, treatment and mortality between Hispanic/Latino (H/L), non-Hispanic Black (NHB) and non-Hispanic White (NHW). Upon discharge post-treatment for STEMI, all patients were followed for a median of 4.4 years (interquartile range 2.5, 6.0). Out of 966 STEMI patients, mean age was 61 years, 46% were H/L and 65% were male. H/Ls and NHBs had a higher prevalence of hypertension and diabetes mellitus than their NHW counterparts, coinciding with a lower socioeconomic status (SES). Results: The number of critically diseased vessels found at cardiac catheterization and mean troponin levels did not vary by race-ethnicity; neither did the adjusted hazard ratios (HR) for death. However, age-sex adjusted rates of general hospital readmission were higher in NHBs vs NHWs (HR 1.30, P=.03). Age-sex adjusted cardiovascular readmissions rates were higher in H/Ls than NHWs (HR 1.42, P=.03). Age-sex adjusted heart failure readmissions were increased for both H/Ls (HR 2.14, P=.01) and NHBs (HR 2.12, P=.02) over NHWs. Conclusions: Among STEMI patients, a higher prevalence of modifiable cardiovascular risk factors and a lower SES was seen among NHBs and H/Ls compared to NHWs. Despite similar coronary disease severity and in-hospital death, NHBs and H/Ls had a greater risk of general, cardiovascular and heart failure readmissions post-STEMI compared to NHWs.
KW - Outcomes
KW - Race-Ethnic Differences
KW - STEMI
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UR - http://www.scopus.com/inward/citedby.url?scp=85135210115&partnerID=8YFLogxK
U2 - 10.18865/ED.32.3.193
DO - 10.18865/ED.32.3.193
M3 - Article
C2 - 35909638
AN - SCOPUS:85135210115
SN - 1049-510X
VL - 32
SP - 193
EP - 202
JO - Ethnicity and Disease
JF - Ethnicity and Disease
IS - 3
ER -