Quantitative changes in serum concentration of bovine gut chitinase in Theileria infection

Wakako Fujimoto, Kazuhiro Kimura, Masako Suzuki, Bunei Syuto, Misao Onuma, Toshihiko Iwanaga

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Bovine gut chitinase is exclusively produced in the liver and secreted into the blood. In the present study, we established a semi-quantitative method by Western blot analysis for measurement of the chitinase content in blood and examined its alteration during postnatal development and experimental infection with hemoprotozoan parasite in cattle. Its serum levels from 1 week to 1 year of age showed a significant increase only in 3-4-month-old group. The plasma concentration of the gut chitinase was not changed during acute inflammation caused by lipopolysaccharide but increased gradually after a Theileria injection and peaked at 52 days post-infection. It appears that the increase in the blood chitinase levels might be a defensive response in cattle against protozoan infection.

Original languageEnglish (US)
Pages (from-to)291-294
Number of pages4
JournalJournal of Veterinary Medical Science
Volume66
Issue number3
DOIs
StatePublished - Mar 1 2004
Externally publishedYes

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Keywords

  • Bovine serum
  • Chitinase
  • Theileria sergenti

ASJC Scopus subject areas

  • veterinary(all)

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