Quality Control: Maintaining molecular order and preventing cellular chaos

Sonya Neal, Fumiaki Ohtake, Ana Maria Cuervo, Ramanujan S. Hegde, Ursula Jakob, Michael Lazarou, Wendy V. Gilbert, Zhijian J. Chen, Sharon A. Tooze, James E. Haber, Kylie J. Walters, F. Ulrich Hartl

Research output: Contribution to journalComment/debatepeer-review

Abstract

We asked experts from different fields—from genome maintenance and proteostasis to organelle degradation via ubiquitin and autophagy—“What does quality control mean to you?” Despite their diverse backgrounds, they converge on and discuss the importance of continuous quality control at all levels, context, communication, timing, decisions on whether to repair or remove, and the significance of dysregulated quality control in disease.

Original languageEnglish (US)
Pages (from-to)1390-1397
Number of pages8
JournalMolecular Cell
Volume82
Issue number8
DOIs
StatePublished - Apr 21 2022

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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