Puzzles, promises and a cure for ageing

Jan Vijg, Judith Campisi

Research output: Contribution to journalReview article

247 Scopus citations

Abstract

Recent discoveries in the science of ageing indicate that lifespan in model organisms such as yeast, nematodes, flies and mice is plastic and can be manipulated by genetic, nutritional or pharmacological intervention. A better understanding of the targets of such interventions, as well as the proximate causes of ageing-related degeneration and disease, is essential before we can evaluate if abrogation of human senescence is a realistic prospect.

Original languageEnglish (US)
Pages (from-to)1065-1071
Number of pages7
JournalNature
Volume454
Issue number7208
DOIs
StatePublished - Aug 28 2008

ASJC Scopus subject areas

  • General

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