Proteins Kinases: Chromatin-Associated Enzymes?

Chi Wing Chow; Roger J. Davis

doi:10.1016/j.cell.2006.11.015

Proteins Kinases: Chromatin-Associated Enzymes?

Chi Wing Chow, Roger J. Davis

Research output: Contribution to journal › Short survey › peer-review

46 Scopus citations

Abstract

Protein kinases contribute to the regulation of gene expression by interacting with transcription factors that are recruited to the regulatory regions of genes. Previous studies investigated the role of protein kinases in transcription initiation. Here, we discuss new insights gleaned from recent work showing that kinases can also interact with chromatin throughout the entire transcribed region of target genes (Pokholok et al., 2006; Proft et al., 2006).

Original language	English (US)
Pages (from-to)	887-890
Number of pages	4
Journal	Cell
Volume	127
Issue number	5
DOIs	https://doi.org/10.1016/j.cell.2006.11.015
State	Published - Dec 1 2006
Externally published	Yes

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1016/j.cell.2006.11.015

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title = "Proteins Kinases: Chromatin-Associated Enzymes?",

abstract = "Protein kinases contribute to the regulation of gene expression by interacting with transcription factors that are recruited to the regulatory regions of genes. Previous studies investigated the role of protein kinases in transcription initiation. Here, we discuss new insights gleaned from recent work showing that kinases can also interact with chromatin throughout the entire transcribed region of target genes (Pokholok et al., 2006; Proft et al., 2006).",

author = "Chow, {Chi Wing} and Davis, {Roger J.}",

year = "2006",

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T1 - Proteins Kinases

T2 - Chromatin-Associated Enzymes?

AU - Chow, Chi Wing

AU - Davis, Roger J.

PY - 2006/12/1

Y1 - 2006/12/1

N2 - Protein kinases contribute to the regulation of gene expression by interacting with transcription factors that are recruited to the regulatory regions of genes. Previous studies investigated the role of protein kinases in transcription initiation. Here, we discuss new insights gleaned from recent work showing that kinases can also interact with chromatin throughout the entire transcribed region of target genes (Pokholok et al., 2006; Proft et al., 2006).

AB - Protein kinases contribute to the regulation of gene expression by interacting with transcription factors that are recruited to the regulatory regions of genes. Previous studies investigated the role of protein kinases in transcription initiation. Here, we discuss new insights gleaned from recent work showing that kinases can also interact with chromatin throughout the entire transcribed region of target genes (Pokholok et al., 2006; Proft et al., 2006).

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U2 - 10.1016/j.cell.2006.11.015

DO - 10.1016/j.cell.2006.11.015

M3 - Short survey

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AN - SCOPUS:33751209494

SN - 0092-8674

VL - 127

SP - 887

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JO - Cell

JF - Cell

IS - 5

ER -

Proteins Kinases: Chromatin-Associated Enzymes?

Abstract

ASJC Scopus subject areas

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