Propylthiouracil inhibits the conversion of L-thyroxine to L-triiodothyronine. An explanation of the antithyroxine effect of propylthiouracil and evidence supporting the concept that triiodothyronine is the active thyroid hormone.

J. H. Oppenheimer, H. L. Schwartz, M. I. Surks

Research output: Contribution to journalArticle

194 Scopus citations
Original languageEnglish (US)
Pages (from-to)2493-2497
Number of pages5
JournalThe Journal of clinical investigation
Volume51
Issue number9
DOIs
StatePublished - Sep 1972
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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