Prognosis for spontaneous resolution of OSA in children

Ronald D. Chervin, Susan S. Ellenberg, Xiaoling Hou, Carole L. Marcus, Susan L. Garetz, Eliot S. Katz, Elise K. Hodges, Ron B. Mitchell, Dwight T. Jones, Raanan Arens, Raouf Amin, Susan Redline, Carol L. Rosen

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

BACKGROUND: Adenotonsillectomy (AT) is commonly performed for childhood OSA syndrome (OSAS), but little is known about prognosis without treatment. METHODS: Th e Childhood Adenotonsillectomy Trial (CHAT) randomized 50% of eligible children with OSAS to a control arm (watchful waiting), with 7-month follow-up symptom inventories, physical examinations, and polysomnography. Polysomnographic and symptomatic resolution were defi ned respectively by an apnea/hypopnea index (AHI), 2 and obstructive apnea index (OAI), 1 and by an OSAS symptom score (Pediatric Sleep Questionnaire [PSQ]), 0.33 with 25% improvement from baseline. RESULTS: Aft er 194 children aged 5 to 9 years underwent 7 months of watchful waiting, 82 (42%) no longer met polysomnographic criteria for OSAS. Baseline predictors of resolution included lower AHI, better oxygen saturation, smaller waist circumference or percentile, higherpositioned soft palate, smaller neck circumference, and non-black race (each P

Original languageEnglish (US)
Pages (from-to)1204-1213
Number of pages10
JournalChest
Volume148
Issue number5
DOIs
StatePublished - Nov 1 2015

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Apnea
Watchful Waiting
Soft Palate
Polysomnography
Waist Circumference
Physical Examination
Sleep
Arm
Neck
Pediatrics
Oxygen
Equipment and Supplies
Therapeutics

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

Cite this

Chervin, R. D., Ellenberg, S. S., Hou, X., Marcus, C. L., Garetz, S. L., Katz, E. S., ... Rosen, C. L. (2015). Prognosis for spontaneous resolution of OSA in children. Chest, 148(5), 1204-1213. https://doi.org/10.1378/chest.14-2873

Prognosis for spontaneous resolution of OSA in children. / Chervin, Ronald D.; Ellenberg, Susan S.; Hou, Xiaoling; Marcus, Carole L.; Garetz, Susan L.; Katz, Eliot S.; Hodges, Elise K.; Mitchell, Ron B.; Jones, Dwight T.; Arens, Raanan; Amin, Raouf; Redline, Susan; Rosen, Carol L.

In: Chest, Vol. 148, No. 5, 01.11.2015, p. 1204-1213.

Research output: Contribution to journalArticle

Chervin, RD, Ellenberg, SS, Hou, X, Marcus, CL, Garetz, SL, Katz, ES, Hodges, EK, Mitchell, RB, Jones, DT, Arens, R, Amin, R, Redline, S & Rosen, CL 2015, 'Prognosis for spontaneous resolution of OSA in children', Chest, vol. 148, no. 5, pp. 1204-1213. https://doi.org/10.1378/chest.14-2873
Chervin RD, Ellenberg SS, Hou X, Marcus CL, Garetz SL, Katz ES et al. Prognosis for spontaneous resolution of OSA in children. Chest. 2015 Nov 1;148(5):1204-1213. https://doi.org/10.1378/chest.14-2873
Chervin, Ronald D. ; Ellenberg, Susan S. ; Hou, Xiaoling ; Marcus, Carole L. ; Garetz, Susan L. ; Katz, Eliot S. ; Hodges, Elise K. ; Mitchell, Ron B. ; Jones, Dwight T. ; Arens, Raanan ; Amin, Raouf ; Redline, Susan ; Rosen, Carol L. / Prognosis for spontaneous resolution of OSA in children. In: Chest. 2015 ; Vol. 148, No. 5. pp. 1204-1213.
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