Primary cytomegalovirus infection with invasive disease in a patient with inflammatory bowel disease

Jingyi Gong, Eric Allan Meyerowitz, Raymond A. Isidro, Kenneth M. Kaye

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

A 37-year-old woman with a history of inflammatory bowel disease on mercaptopurine presented with a week of recurrent fever, headache, myalgias and mildly elevated serum transaminases and leucopenia. Her workup revealed primary cytomegalovirus (CMV) infection with atypical lymphocytosis, elevated viral load, positive IgM and negative IgG. Two weeks after her initial presentation, she developed odynophagia and diarrhoea prompting endoscopic evaluation with biopsies, which demonstrated CMV disease of the gastrointestinal tract. Her fever and systemic symptoms improved rapidly with initiation of intravenous ganciclovir. She was transitioned to and maintained on oral valganciclovir until two and half months after discharge when her symptoms and lab abnormalities had fully subsided.

Original languageEnglish (US)
Article numbere230056
JournalBMJ case reports
Volume12
Issue number9
DOIs
StatePublished - Sep 1 2019
Externally publishedYes

Keywords

  • infection (gastroenterology)
  • infections
  • infectious diseases
  • inflammatory bowel disease
  • pathology

ASJC Scopus subject areas

  • Medicine(all)

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