Primary Central Nervous System Lymphomas

Jerome J. Graber, Antonio M P Omuro

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Primary CNS lymphoma (PCNSL) is a non-Hodgkin lymphoma that may develop in both immunocompetent and immunosuppressed patients. Early suspicion based on imaging characteristics may improve diagnostic accuracy, avoid inappropriate interventions, and expedite appropriate therapy. Treatment with high dose methotrexate-based chemotherapy, with or without radiotherapy, may result in long-term survival in up to 25% of patients. However, the optimal regimen remains to be determined, and disease relapses and treatment-related CNS neurotoxicity remain common.

Original languageEnglish (US)
Title of host publicationNeuro-oncology: First Edition
PublisherBlackwell Publishing Ltd.
Pages125-133
Number of pages9
ISBN (Print)9780470655757
DOIs
StatePublished - Feb 29 2012

Fingerprint

Lymphoma
Central Nervous System
Methotrexate
Non-Hodgkin's Lymphoma
Radiotherapy
Therapeutics
Recurrence
Drug Therapy
Survival

Keywords

  • Methotrexate
  • Ocular lymphoma
  • Primary central nervous system lymphoma

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Graber, J. J., & Omuro, A. M. P. (2012). Primary Central Nervous System Lymphomas. In Neuro-oncology: First Edition (pp. 125-133). Blackwell Publishing Ltd.. https://doi.org/10.1002/9781118321478.ch12

Primary Central Nervous System Lymphomas. / Graber, Jerome J.; Omuro, Antonio M P.

Neuro-oncology: First Edition. Blackwell Publishing Ltd., 2012. p. 125-133.

Research output: Chapter in Book/Report/Conference proceedingChapter

Graber, JJ & Omuro, AMP 2012, Primary Central Nervous System Lymphomas. in Neuro-oncology: First Edition. Blackwell Publishing Ltd., pp. 125-133. https://doi.org/10.1002/9781118321478.ch12
Graber JJ, Omuro AMP. Primary Central Nervous System Lymphomas. In Neuro-oncology: First Edition. Blackwell Publishing Ltd. 2012. p. 125-133 https://doi.org/10.1002/9781118321478.ch12
Graber, Jerome J. ; Omuro, Antonio M P. / Primary Central Nervous System Lymphomas. Neuro-oncology: First Edition. Blackwell Publishing Ltd., 2012. pp. 125-133
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