Abstract
We report a case of recurrent priapism in a sickle cell patient who had undergone physiological transformation from a low-flow state to a mixed high-flow/low-flow picture. An oral alpha-adrenergic agonist/histamine-1 antagonist combination maintained a balance of potency without stutter in the latter state, whereas an oral alpha-adrenergic agonist in the early part of his course did not prevent priapic progression. Concomitant use of a non-steroidal anti-androgenic agent rendered him impotent despite good libido. Other etiologies should be considered in the setting of recurrent priapism and failed standard therapies; duplex ultrasound is useful in order to delineate the hemodynamics. This case supports contentions that priapism is a spectrum phenomenon, and raises questions regarding the mechanism by which alpha-adrenergic agents prevent priapic progression.
Original language | English (US) |
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Pages (from-to) | 59-63 |
Number of pages | 5 |
Journal | International journal of impotence research |
Volume | 12 |
Issue number | 1 |
DOIs | |
State | Published - 2000 |
Externally published | Yes |
Keywords
- Alpha-adrenergic agonist
- Duplex ultrasound
- Histamine antagonist
- Nonsteroidal anti-androgen
- Priapism
- Sickle cell anemia
ASJC Scopus subject areas
- Urology