Abstract
We report a case of recurrent priapism in a sickle cell patient who had undergone physiological transformation from a low-flow state to a mixed high-flow/low-flow picture. An oral alpha-adrenergic agonist/histamine-1 antagonist combination maintained a balance of potency without stutter in the latter state, whereas an oral alpha-adrenergic agonist in the early part of his course did not prevent priapic progression. Concomitant use of a non-steroidal anti-androgenic agent rendered him impotent despite good libido. Other etiologies should be considered in the setting of recurrent priapism and failed standard therapies; duplex ultrasound is useful in order to delineate the hemodynamics. This case supports contentions that priapism is a spectrum phenomenon, and raises questions regarding the mechanism by which alpha-adrenergic agents prevent priapic progression.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 59-63 |
| Number of pages | 5 |
| Journal | International Journal of Impotence Research |
| Volume | 12 |
| Issue number | 1 |
| State | Published - 2000 |
Fingerprint
Keywords
- Alpha-adrenergic agonist
- Duplex ultrasound
- Histamine antagonist
- Nonsteroidal anti-androgen
- Priapism
- Sickle cell anemia
ASJC Scopus subject areas
- Urology
Cite this
Priapism of ambiguous classification in a sickle cell patient. / Huffman, S.; Kaynan, A. M.; Melman, A.
In: International Journal of Impotence Research, Vol. 12, No. 1, 2000, p. 59-63.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Priapism of ambiguous classification in a sickle cell patient
AU - Huffman, S.
AU - Kaynan, A. M.
AU - Melman, A.
PY - 2000
Y1 - 2000
N2 - We report a case of recurrent priapism in a sickle cell patient who had undergone physiological transformation from a low-flow state to a mixed high-flow/low-flow picture. An oral alpha-adrenergic agonist/histamine-1 antagonist combination maintained a balance of potency without stutter in the latter state, whereas an oral alpha-adrenergic agonist in the early part of his course did not prevent priapic progression. Concomitant use of a non-steroidal anti-androgenic agent rendered him impotent despite good libido. Other etiologies should be considered in the setting of recurrent priapism and failed standard therapies; duplex ultrasound is useful in order to delineate the hemodynamics. This case supports contentions that priapism is a spectrum phenomenon, and raises questions regarding the mechanism by which alpha-adrenergic agents prevent priapic progression.
AB - We report a case of recurrent priapism in a sickle cell patient who had undergone physiological transformation from a low-flow state to a mixed high-flow/low-flow picture. An oral alpha-adrenergic agonist/histamine-1 antagonist combination maintained a balance of potency without stutter in the latter state, whereas an oral alpha-adrenergic agonist in the early part of his course did not prevent priapic progression. Concomitant use of a non-steroidal anti-androgenic agent rendered him impotent despite good libido. Other etiologies should be considered in the setting of recurrent priapism and failed standard therapies; duplex ultrasound is useful in order to delineate the hemodynamics. This case supports contentions that priapism is a spectrum phenomenon, and raises questions regarding the mechanism by which alpha-adrenergic agents prevent priapic progression.
KW - Alpha-adrenergic agonist
KW - Duplex ultrasound
KW - Histamine antagonist
KW - Nonsteroidal anti-androgen
KW - Priapism
KW - Sickle cell anemia
UR - http://www.scopus.com/inward/record.url?scp=0033930945&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033930945&partnerID=8YFLogxK
M3 - Article
C2 - 10982314
AN - SCOPUS:0033930945
VL - 12
SP - 59
EP - 63
JO - International Journal of Impotence Research
JF - International Journal of Impotence Research
SN - 0955-9930
IS - 1
ER -