Priapism of ambiguous classification in a sickle cell patient

S. Huffman, A. M. Kaynan, A. Melman

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We report a case of recurrent priapism in a sickle cell patient who had undergone physiological transformation from a low-flow state to a mixed high-flow/low-flow picture. An oral alpha-adrenergic agonist/histamine-1 antagonist combination maintained a balance of potency without stutter in the latter state, whereas an oral alpha-adrenergic agonist in the early part of his course did not prevent priapic progression. Concomitant use of a non-steroidal anti-androgenic agent rendered him impotent despite good libido. Other etiologies should be considered in the setting of recurrent priapism and failed standard therapies; duplex ultrasound is useful in order to delineate the hemodynamics. This case supports contentions that priapism is a spectrum phenomenon, and raises questions regarding the mechanism by which alpha-adrenergic agents prevent priapic progression.

Original languageEnglish (US)
Pages (from-to)59-63
Number of pages5
JournalInternational Journal of Impotence Research
Volume12
Issue number1
StatePublished - 2000

Fingerprint

Priapism
Adrenergic alpha-1 Receptor Agonists
Adrenergic alpha-Agonists
Libido
Histamine Antagonists
Adrenergic Agents
Androgens
Hemodynamics
Therapeutics

Keywords

  • Alpha-adrenergic agonist
  • Duplex ultrasound
  • Histamine antagonist
  • Nonsteroidal anti-androgen
  • Priapism
  • Sickle cell anemia

ASJC Scopus subject areas

  • Urology

Cite this

Priapism of ambiguous classification in a sickle cell patient. / Huffman, S.; Kaynan, A. M.; Melman, A.

In: International Journal of Impotence Research, Vol. 12, No. 1, 2000, p. 59-63.

Research output: Contribution to journalArticle

Huffman, S, Kaynan, AM & Melman, A 2000, 'Priapism of ambiguous classification in a sickle cell patient', International Journal of Impotence Research, vol. 12, no. 1, pp. 59-63.
Huffman, S. ; Kaynan, A. M. ; Melman, A. / Priapism of ambiguous classification in a sickle cell patient. In: International Journal of Impotence Research. 2000 ; Vol. 12, No. 1. pp. 59-63.
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