Priapism

A. Melman, S. Serels, [No Value] Morales, [No Value] Wessells, [No Value] Mulcahy, [No Value] Lewis, [No Value] Pryor

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Priapism is a prolonged, painful, penile erection that fails to subside despite orgasm. An erection lasting longer than 4-6 h is considered to be priapic; nevertheless, pain does not usually ensue until 6-8 h have elapsed. Priapism is considered a failure of the detumescence mechanism, which may be due to excess release of contractile neurotransmitters, obstruction of draining venules, malfunction of the intrinsic detumescence mechanism, or prolonged relaxation of intracavernosal smooth muscle. There are essentially two main types of priapism: high flow (non-ischemic) and low flow (ischemic). Low flow priapism is the more common form, and it is associated with a decrease in venous outflow and vascular stasis that, in turn, cause tissue hypoxia and acidosis. This form of priapism is usually quite painful because of tissue ischemia. Penile blood aspirated from cavernous spaces appears dark in color. Immediate treatment is necessary or penile fibrosis will ensue. High flow priapism is usually due to trauma, although, on rare occasions it has been idiopathic or due to sickle cell disease. The hallmark of this type of priapism is an increase in arterial inflow in the setting of normal venous outflow. Aspirated penile blood is noted to be bright red and has a high pO2. This form of priapism is not usually painful because it is non-ischemic. Treatment is dependent on the wishes of the patient but is not mandatory.

Original languageEnglish (US)
JournalInternational Journal of Impotence Research
Volume12
Issue numberSUPPL. 4
StatePublished - 2000

Fingerprint

Priapism
Orgasm
Penile Erection
Venules
Sickle Cell Anemia
Acidosis
Smooth Muscle
Neurotransmitter Agents
Blood Vessels
Fibrosis
Ischemia
Color
Pain
Wounds and Injuries

Keywords

  • High-flow priapism
  • Low-flow priapism
  • Penile blood flow
  • Sickle-cell disease
  • Tissue hypoxia

ASJC Scopus subject areas

  • Urology

Cite this

Melman, A., Serels, S., Morales, N. V., Wessells, N. V., Mulcahy, N. V., Lewis, N. V., & Pryor, N. V. (2000). Priapism. International Journal of Impotence Research, 12(SUPPL. 4).

Priapism. / Melman, A.; Serels, S.; Morales, [No Value]; Wessells, [No Value]; Mulcahy, [No Value]; Lewis, [No Value]; Pryor, [No Value].

In: International Journal of Impotence Research, Vol. 12, No. SUPPL. 4, 2000.

Research output: Contribution to journalArticle

Melman, A, Serels, S, Morales, NV, Wessells, NV, Mulcahy, NV, Lewis, NV & Pryor, NV 2000, 'Priapism', International Journal of Impotence Research, vol. 12, no. SUPPL. 4.
Melman A, Serels S, Morales NV, Wessells NV, Mulcahy NV, Lewis NV et al. Priapism. International Journal of Impotence Research. 2000;12(SUPPL. 4).
Melman, A. ; Serels, S. ; Morales, [No Value] ; Wessells, [No Value] ; Mulcahy, [No Value] ; Lewis, [No Value] ; Pryor, [No Value]. / Priapism. In: International Journal of Impotence Research. 2000 ; Vol. 12, No. SUPPL. 4.
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