Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)

Bernardo Dell’Osso, Beatrice Benatti, Chiara Arici, Carlotta Palazzo, A. Carlo Altamura, Eric Hollander, Naomi Fineberg, Dan J. Stein, Humberto Nicolini, Nuria Lanzagorta, Donatella Marazziti, Stefano Pallanti, Michael van Ameringen, Christine Lochner, Oguz Karamustafalioglu, Luchezar Hranov, Martijn Figee, Lynne Drummond, Carolyn I. Rodriguez, John GrantDamiaan Denys, Jose M. Menchon, Joseph Zohar

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Objective: Obsessive-compulsive disorder (OCD) is associated with variable risk of suicide and prevalence of suicide attempt (SA). The present study aimed to assess the prevalence of SA and associated sociodemographic and clinical features in a large international sample of OCD patients. Methods: A total of 425 OCD outpatients, recruited through the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) network, were assessed and categorized in groups with or without a history of SA, and their sociodemographic and clinical features compared through Pearson’s chi-squared and t tests. Logistic regression was performed to assess the impact of the collected data on the SA variable. Results: 14.6% of our sample reported at least one SA during their lifetime. Patients with an SA had significantly higher rates of comorbid psychiatric disorders (60 vs. 17%, p<0.001; particularly tic disorder), medical disorders (51 vs. 15%, p<0.001), and previous hospitalizations (62 vs. 11%, p<0.001) than patients with no history of SA. With respect to geographical differences, European and South African patients showed significantly higher rates of SA history (40 and 39%, respectively) compared to North American and Middle-Eastern individuals (13 and 8%, respectively) (χ2=11.4, p<0.001). The logistic regression did not show any statistically significant predictor of SA among selected independent variables. Conclusions: Our international study found a history of SA prevalence of ~15% in OCD patients, with higher rates of psychiatric and medical comorbidities and previous hospitalizations in patients with a previous SA. Along with potential geographical influences, the presence of the abovementioned features should recommend additional caution in the assessment of suicide risk in OCD patients.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalCNS Spectrums
DOIs
StateAccepted/In press - Mar 16 2017

Fingerprint

Obsessive-Compulsive Disorder
Suicide
Psychiatry
Hospitalization
Logistic Models
Tic Disorders
Comorbidity
Outpatients
History

Keywords

  • comorbidity
  • hospitalization
  • Obsessive-compulsive disorder
  • prevalence
  • suicide attempt

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health

Cite this

Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder : a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS). / Dell’Osso, Bernardo; Benatti, Beatrice; Arici, Chiara; Palazzo, Carlotta; Altamura, A. Carlo; Hollander, Eric; Fineberg, Naomi; Stein, Dan J.; Nicolini, Humberto; Lanzagorta, Nuria; Marazziti, Donatella; Pallanti, Stefano; van Ameringen, Michael; Lochner, Christine; Karamustafalioglu, Oguz; Hranov, Luchezar; Figee, Martijn; Drummond, Lynne; Rodriguez, Carolyn I.; Grant, John; Denys, Damiaan; Menchon, Jose M.; Zohar, Joseph.

In: CNS Spectrums, 16.03.2017, p. 1-8.

Research output: Contribution to journalArticle

Dell’Osso, B, Benatti, B, Arici, C, Palazzo, C, Altamura, AC, Hollander, E, Fineberg, N, Stein, DJ, Nicolini, H, Lanzagorta, N, Marazziti, D, Pallanti, S, van Ameringen, M, Lochner, C, Karamustafalioglu, O, Hranov, L, Figee, M, Drummond, L, Rodriguez, CI, Grant, J, Denys, D, Menchon, JM & Zohar, J 2017, 'Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)', CNS Spectrums, pp. 1-8. https://doi.org/10.1017/S1092852917000177
Dell’Osso, Bernardo ; Benatti, Beatrice ; Arici, Chiara ; Palazzo, Carlotta ; Altamura, A. Carlo ; Hollander, Eric ; Fineberg, Naomi ; Stein, Dan J. ; Nicolini, Humberto ; Lanzagorta, Nuria ; Marazziti, Donatella ; Pallanti, Stefano ; van Ameringen, Michael ; Lochner, Christine ; Karamustafalioglu, Oguz ; Hranov, Luchezar ; Figee, Martijn ; Drummond, Lynne ; Rodriguez, Carolyn I. ; Grant, John ; Denys, Damiaan ; Menchon, Jose M. ; Zohar, Joseph. / Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder : a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS). In: CNS Spectrums. 2017 ; pp. 1-8.
@article{690894dddf8c47a1ab2159f85b2860de,
title = "Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder: a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)",
abstract = "Objective: Obsessive-compulsive disorder (OCD) is associated with variable risk of suicide and prevalence of suicide attempt (SA). The present study aimed to assess the prevalence of SA and associated sociodemographic and clinical features in a large international sample of OCD patients. Methods: A total of 425 OCD outpatients, recruited through the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) network, were assessed and categorized in groups with or without a history of SA, and their sociodemographic and clinical features compared through Pearson’s chi-squared and t tests. Logistic regression was performed to assess the impact of the collected data on the SA variable. Results: 14.6{\%} of our sample reported at least one SA during their lifetime. Patients with an SA had significantly higher rates of comorbid psychiatric disorders (60 vs. 17{\%}, p<0.001; particularly tic disorder), medical disorders (51 vs. 15{\%}, p<0.001), and previous hospitalizations (62 vs. 11{\%}, p<0.001) than patients with no history of SA. With respect to geographical differences, European and South African patients showed significantly higher rates of SA history (40 and 39{\%}, respectively) compared to North American and Middle-Eastern individuals (13 and 8{\%}, respectively) (χ2=11.4, p<0.001). The logistic regression did not show any statistically significant predictor of SA among selected independent variables. Conclusions: Our international study found a history of SA prevalence of ~15{\%} in OCD patients, with higher rates of psychiatric and medical comorbidities and previous hospitalizations in patients with a previous SA. Along with potential geographical influences, the presence of the abovementioned features should recommend additional caution in the assessment of suicide risk in OCD patients.",
keywords = "comorbidity, hospitalization, Obsessive-compulsive disorder, prevalence, suicide attempt",
author = "Bernardo Dell’Osso and Beatrice Benatti and Chiara Arici and Carlotta Palazzo and Altamura, {A. Carlo} and Eric Hollander and Naomi Fineberg and Stein, {Dan J.} and Humberto Nicolini and Nuria Lanzagorta and Donatella Marazziti and Stefano Pallanti and {van Ameringen}, Michael and Christine Lochner and Oguz Karamustafalioglu and Luchezar Hranov and Martijn Figee and Lynne Drummond and Rodriguez, {Carolyn I.} and John Grant and Damiaan Denys and Menchon, {Jose M.} and Joseph Zohar",
year = "2017",
month = "3",
day = "16",
doi = "10.1017/S1092852917000177",
language = "English (US)",
pages = "1--8",
journal = "CNS Spectrums",
issn = "1092-8529",
publisher = "MBL Communications",

}

TY - JOUR

T1 - Prevalence of suicide attempt and clinical characteristics of suicide attempters with obsessive-compulsive disorder

T2 - a report from the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS)

AU - Dell’Osso, Bernardo

AU - Benatti, Beatrice

AU - Arici, Chiara

AU - Palazzo, Carlotta

AU - Altamura, A. Carlo

AU - Hollander, Eric

AU - Fineberg, Naomi

AU - Stein, Dan J.

AU - Nicolini, Humberto

AU - Lanzagorta, Nuria

AU - Marazziti, Donatella

AU - Pallanti, Stefano

AU - van Ameringen, Michael

AU - Lochner, Christine

AU - Karamustafalioglu, Oguz

AU - Hranov, Luchezar

AU - Figee, Martijn

AU - Drummond, Lynne

AU - Rodriguez, Carolyn I.

AU - Grant, John

AU - Denys, Damiaan

AU - Menchon, Jose M.

AU - Zohar, Joseph

PY - 2017/3/16

Y1 - 2017/3/16

N2 - Objective: Obsessive-compulsive disorder (OCD) is associated with variable risk of suicide and prevalence of suicide attempt (SA). The present study aimed to assess the prevalence of SA and associated sociodemographic and clinical features in a large international sample of OCD patients. Methods: A total of 425 OCD outpatients, recruited through the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) network, were assessed and categorized in groups with or without a history of SA, and their sociodemographic and clinical features compared through Pearson’s chi-squared and t tests. Logistic regression was performed to assess the impact of the collected data on the SA variable. Results: 14.6% of our sample reported at least one SA during their lifetime. Patients with an SA had significantly higher rates of comorbid psychiatric disorders (60 vs. 17%, p<0.001; particularly tic disorder), medical disorders (51 vs. 15%, p<0.001), and previous hospitalizations (62 vs. 11%, p<0.001) than patients with no history of SA. With respect to geographical differences, European and South African patients showed significantly higher rates of SA history (40 and 39%, respectively) compared to North American and Middle-Eastern individuals (13 and 8%, respectively) (χ2=11.4, p<0.001). The logistic regression did not show any statistically significant predictor of SA among selected independent variables. Conclusions: Our international study found a history of SA prevalence of ~15% in OCD patients, with higher rates of psychiatric and medical comorbidities and previous hospitalizations in patients with a previous SA. Along with potential geographical influences, the presence of the abovementioned features should recommend additional caution in the assessment of suicide risk in OCD patients.

AB - Objective: Obsessive-compulsive disorder (OCD) is associated with variable risk of suicide and prevalence of suicide attempt (SA). The present study aimed to assess the prevalence of SA and associated sociodemographic and clinical features in a large international sample of OCD patients. Methods: A total of 425 OCD outpatients, recruited through the International College of Obsessive-Compulsive Spectrum Disorders (ICOCS) network, were assessed and categorized in groups with or without a history of SA, and their sociodemographic and clinical features compared through Pearson’s chi-squared and t tests. Logistic regression was performed to assess the impact of the collected data on the SA variable. Results: 14.6% of our sample reported at least one SA during their lifetime. Patients with an SA had significantly higher rates of comorbid psychiatric disorders (60 vs. 17%, p<0.001; particularly tic disorder), medical disorders (51 vs. 15%, p<0.001), and previous hospitalizations (62 vs. 11%, p<0.001) than patients with no history of SA. With respect to geographical differences, European and South African patients showed significantly higher rates of SA history (40 and 39%, respectively) compared to North American and Middle-Eastern individuals (13 and 8%, respectively) (χ2=11.4, p<0.001). The logistic regression did not show any statistically significant predictor of SA among selected independent variables. Conclusions: Our international study found a history of SA prevalence of ~15% in OCD patients, with higher rates of psychiatric and medical comorbidities and previous hospitalizations in patients with a previous SA. Along with potential geographical influences, the presence of the abovementioned features should recommend additional caution in the assessment of suicide risk in OCD patients.

KW - comorbidity

KW - hospitalization

KW - Obsessive-compulsive disorder

KW - prevalence

KW - suicide attempt

UR - http://www.scopus.com/inward/record.url?scp=85015622799&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85015622799&partnerID=8YFLogxK

U2 - 10.1017/S1092852917000177

DO - 10.1017/S1092852917000177

M3 - Article

C2 - 28300008

AN - SCOPUS:85015622799

SP - 1

EP - 8

JO - CNS Spectrums

JF - CNS Spectrums

SN - 1092-8529

ER -