Prevalence of right ventricular perfusion defects after inferior myocardial infarction assessed by low-level exercise with technetium 99m sestamibi tomographic myocardial imaging

Mark I. Travin, Robert D. Malkin, Carol Ewing Garber, Debra E. Messinger, Donna J. Cloutier, Gary V. Heller

Research output: Contribution to journalArticle

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Abstract

To assess the prevalence of right ventricular perfusion defects after a recent inferior wall myocardial infarction, 33 patients were studied 6 to 14 days after infarction with low-level exercise testing and technetium 99m (99mTc) sestamibi (SPECT) imaging. Twenty-two control subjects with a <5% likelihood of coronary artery disease undergoing exercise 99mTc sestamibi imaging were also studied. For each image the right ventricle was computer isolated from reconstructed transverse cardiac slices, followed by reorientation into oblique slices. Both right and left ventricular images were visually assessed for defects. A quantitative method of defect detection was also applied to the right ventricle. For the right ventricle, 100% of the stress images and 96% of the rest images were adequate for interpretation. Right ventricular stress perfusion defects were identified in 10 (30%) of 33 patients with recent inferior infarction, with 50% completely or partially normalizing on rest images, consistent with ischemia. Of 14 patients with left ventricular inferoseptal defects, eitht (57%) had right ventricular defects compared with 2 (11%) of 19 without inferoseptal defects (p < 0.005). We concluded that the right ventricle can be adequately assessed for perfusion defects by means of exercise with 99mTc sestamibi SPECT imaging. Defects of the right ventricle after inferior myocardial infarction occur frequently, and many have evidence of ischemia. Right ventricular perfusion defects are closely associated with left ventricular inferoseptal defects.

Original languageEnglish (US)
Pages (from-to)797-804
Number of pages8
JournalAmerican Heart Journal
Volume127
Issue number4 PART 1
DOIs
StatePublished - 1994
Externally publishedYes

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Inferior Wall Myocardial Infarction
Technetium Tc 99m Sestamibi
Heart Ventricles
Perfusion
Exercise
Single-Photon Emission-Computed Tomography
Infarction
Ischemia
Coronary Artery Disease

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Prevalence of right ventricular perfusion defects after inferior myocardial infarction assessed by low-level exercise with technetium 99m sestamibi tomographic myocardial imaging. / Travin, Mark I.; Malkin, Robert D.; Garber, Carol Ewing; Messinger, Debra E.; Cloutier, Donna J.; Heller, Gary V.

In: American Heart Journal, Vol. 127, No. 4 PART 1, 1994, p. 797-804.

Research output: Contribution to journalArticle

Travin, Mark I. ; Malkin, Robert D. ; Garber, Carol Ewing ; Messinger, Debra E. ; Cloutier, Donna J. ; Heller, Gary V. / Prevalence of right ventricular perfusion defects after inferior myocardial infarction assessed by low-level exercise with technetium 99m sestamibi tomographic myocardial imaging. In: American Heart Journal. 1994 ; Vol. 127, No. 4 PART 1. pp. 797-804.
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