Prevalence of dry eye in Bangkok, Thailand

Kaevalin Lekhanont, Duangnate Rojanaporn, Roy S. Chuck, Anun Vongthongsri

Research output: Contribution to journalArticle

111 Citations (Scopus)

Abstract

PURPOSE: To estimate the prevalence of dry eye in the adult population of Bangkok, Thailand. METHODS: Five hundred fifty volunteers 40 years of age or more who presented to the Ramathibodi Hospital for annual eye examinations were enrolled. Interviewers administered a dry eye symptoms questionnaire. Slit-lamp examination and objective dry eye assessment consisting of tear film breakup time (TBUT), fluorescein corneal staining, Schirmer tests, and meibomian gland evaluation were performed. Outcome measures included frequency of symptoms and positive dry eye tests. RESULTS: Thirty-four percent reported significant symptoms, which were defined as having one or more symptoms often or all of the time (95% confidence interval, 28.1-40.6). Approximately one half had meibomian gland disease (MGD) or pingueculum/pterygium (46.2 and 53.8%, respectively). Individuals with significant symptoms tended to be women (83.4%, P = 0.024), had MGD (63.6%, P = 0.006), had current artificial tear use (33.2%, P = 0.024), and had positive TBUT (80.7%, P = 0.000) and fluorescein staining (16.6%, P = 0.013.) The presence of pingueculum/pterygium and MGD were significantly associated with positive dry eye tests. CONCLUSION: This is the first report of prevalence of dry eye inclusive of signs and symptoms in an elderly Thai population. The prevalence of disease diagnosed on the basis of symptoms and dry eye tests was approximately 2 to 3 times higher than reported in whites. Women were more likely to report symptoms. Positive associations with dry eye tests were found in subjects with pingueculum/pterygium and MGD.

Original languageEnglish (US)
Pages (from-to)1162-1167
Number of pages6
JournalCornea
Volume25
Issue number10
DOIs
StatePublished - Dec 2006
Externally publishedYes

Fingerprint

Thailand
Meibomian Glands
Pterygium
Fluorescein
Tears
Staining and Labeling
Population
Signs and Symptoms
Volunteers
Outcome Assessment (Health Care)
Confidence Intervals
Interviews

Keywords

  • Dry eye
  • Prevalence
  • Thai population

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Lekhanont, K., Rojanaporn, D., Chuck, R. S., & Vongthongsri, A. (2006). Prevalence of dry eye in Bangkok, Thailand. Cornea, 25(10), 1162-1167. https://doi.org/10.1097/01.ico.0000244875.92879.1a

Prevalence of dry eye in Bangkok, Thailand. / Lekhanont, Kaevalin; Rojanaporn, Duangnate; Chuck, Roy S.; Vongthongsri, Anun.

In: Cornea, Vol. 25, No. 10, 12.2006, p. 1162-1167.

Research output: Contribution to journalArticle

Lekhanont, K, Rojanaporn, D, Chuck, RS & Vongthongsri, A 2006, 'Prevalence of dry eye in Bangkok, Thailand', Cornea, vol. 25, no. 10, pp. 1162-1167. https://doi.org/10.1097/01.ico.0000244875.92879.1a
Lekhanont K, Rojanaporn D, Chuck RS, Vongthongsri A. Prevalence of dry eye in Bangkok, Thailand. Cornea. 2006 Dec;25(10):1162-1167. https://doi.org/10.1097/01.ico.0000244875.92879.1a
Lekhanont, Kaevalin ; Rojanaporn, Duangnate ; Chuck, Roy S. ; Vongthongsri, Anun. / Prevalence of dry eye in Bangkok, Thailand. In: Cornea. 2006 ; Vol. 25, No. 10. pp. 1162-1167.
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N2 - PURPOSE: To estimate the prevalence of dry eye in the adult population of Bangkok, Thailand. METHODS: Five hundred fifty volunteers 40 years of age or more who presented to the Ramathibodi Hospital for annual eye examinations were enrolled. Interviewers administered a dry eye symptoms questionnaire. Slit-lamp examination and objective dry eye assessment consisting of tear film breakup time (TBUT), fluorescein corneal staining, Schirmer tests, and meibomian gland evaluation were performed. Outcome measures included frequency of symptoms and positive dry eye tests. RESULTS: Thirty-four percent reported significant symptoms, which were defined as having one or more symptoms often or all of the time (95% confidence interval, 28.1-40.6). Approximately one half had meibomian gland disease (MGD) or pingueculum/pterygium (46.2 and 53.8%, respectively). Individuals with significant symptoms tended to be women (83.4%, P = 0.024), had MGD (63.6%, P = 0.006), had current artificial tear use (33.2%, P = 0.024), and had positive TBUT (80.7%, P = 0.000) and fluorescein staining (16.6%, P = 0.013.) The presence of pingueculum/pterygium and MGD were significantly associated with positive dry eye tests. CONCLUSION: This is the first report of prevalence of dry eye inclusive of signs and symptoms in an elderly Thai population. The prevalence of disease diagnosed on the basis of symptoms and dry eye tests was approximately 2 to 3 times higher than reported in whites. Women were more likely to report symptoms. Positive associations with dry eye tests were found in subjects with pingueculum/pterygium and MGD.

AB - PURPOSE: To estimate the prevalence of dry eye in the adult population of Bangkok, Thailand. METHODS: Five hundred fifty volunteers 40 years of age or more who presented to the Ramathibodi Hospital for annual eye examinations were enrolled. Interviewers administered a dry eye symptoms questionnaire. Slit-lamp examination and objective dry eye assessment consisting of tear film breakup time (TBUT), fluorescein corneal staining, Schirmer tests, and meibomian gland evaluation were performed. Outcome measures included frequency of symptoms and positive dry eye tests. RESULTS: Thirty-four percent reported significant symptoms, which were defined as having one or more symptoms often or all of the time (95% confidence interval, 28.1-40.6). Approximately one half had meibomian gland disease (MGD) or pingueculum/pterygium (46.2 and 53.8%, respectively). Individuals with significant symptoms tended to be women (83.4%, P = 0.024), had MGD (63.6%, P = 0.006), had current artificial tear use (33.2%, P = 0.024), and had positive TBUT (80.7%, P = 0.000) and fluorescein staining (16.6%, P = 0.013.) The presence of pingueculum/pterygium and MGD were significantly associated with positive dry eye tests. CONCLUSION: This is the first report of prevalence of dry eye inclusive of signs and symptoms in an elderly Thai population. The prevalence of disease diagnosed on the basis of symptoms and dry eye tests was approximately 2 to 3 times higher than reported in whites. Women were more likely to report symptoms. Positive associations with dry eye tests were found in subjects with pingueculum/pterygium and MGD.

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