TY - JOUR
T1 - Prevalence of Cochlear-Facial Dehiscence in a Study of 1,020 Temporal Bone Specimens
AU - Fang, Christina H.
AU - Chung, Sei Yeon
AU - Blake, Danielle M.
AU - Vazquez, Alejandro
AU - Li, Chengrui
AU - Carey, John P.
AU - Francis, Howard W.
AU - Jyung, Robert W.
N1 - Publisher Copyright:
Copyright © 2016 Otology & Neurotology, Inc.
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Objective: To determine the prevalence of cochlear-facial dehiscence (CFD) and to examine the influence of otic capsule area, age, sex, and race on CFD. Study Design: Descriptive study of archived temporal bone specimens. Materials and Methods: Targeted sections from 1,020 temporal bone specimens were scanned and examined for CFD. Cochlear-facial partition width (CFPW) and otic capsule area (OCA), a marker of bone thickness, were measured using image analysis software. Demographic data were analyzed using multiple linear regression analysis. Results: The mean CFPW was 0.23 mm (range, 0-0.92 mm; SD, 0.15 mm). Six patients were completely dehiscent (0.59%). Fallopian canal width, age, sex, race, and OCA were found to be significant predictors of CFPW. Age was found to be negatively correlated with CFPW (β = -0.001) (p < 0.005). Thicker CFPW was associated with males (β = 0.024) and non-Caucasian individuals (β = 0.031). The mean OCA for dehiscent specimens (mean, 9.48 mm 2; range, 6.65-11.58 mm 2; SD 3.21 mm 2) was significantly smaller than the mean OCA for nondehiscent specimens, (mean, 12.88 mm 2; range, 6.63-21.92 mm 2; SD, 2.47 mm 2) (p < 0.01). Conclusion: CFD occurred in nearly 0.6% of specimens in this temporal bone collection. Close to 35% of patients were sufficiently thin (<0.1 mm) to appear dehiscent on computed tomography scanning. Smaller OCA correlated with thinner CFPW, suggesting a developmental factor. Older, female, and Caucasian patients may have a greater risk for CFD and its associated symptoms.
AB - Objective: To determine the prevalence of cochlear-facial dehiscence (CFD) and to examine the influence of otic capsule area, age, sex, and race on CFD. Study Design: Descriptive study of archived temporal bone specimens. Materials and Methods: Targeted sections from 1,020 temporal bone specimens were scanned and examined for CFD. Cochlear-facial partition width (CFPW) and otic capsule area (OCA), a marker of bone thickness, were measured using image analysis software. Demographic data were analyzed using multiple linear regression analysis. Results: The mean CFPW was 0.23 mm (range, 0-0.92 mm; SD, 0.15 mm). Six patients were completely dehiscent (0.59%). Fallopian canal width, age, sex, race, and OCA were found to be significant predictors of CFPW. Age was found to be negatively correlated with CFPW (β = -0.001) (p < 0.005). Thicker CFPW was associated with males (β = 0.024) and non-Caucasian individuals (β = 0.031). The mean OCA for dehiscent specimens (mean, 9.48 mm 2; range, 6.65-11.58 mm 2; SD 3.21 mm 2) was significantly smaller than the mean OCA for nondehiscent specimens, (mean, 12.88 mm 2; range, 6.63-21.92 mm 2; SD, 2.47 mm 2) (p < 0.01). Conclusion: CFD occurred in nearly 0.6% of specimens in this temporal bone collection. Close to 35% of patients were sufficiently thin (<0.1 mm) to appear dehiscent on computed tomography scanning. Smaller OCA correlated with thinner CFPW, suggesting a developmental factor. Older, female, and Caucasian patients may have a greater risk for CFD and its associated symptoms.
KW - Cochlear facial dehiscence
KW - Otic capsule dehiscence
KW - Otic capsule development
KW - Pseudoconductive hearing loss
KW - Sensorineural hearing loss
KW - Temporal bone study
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U2 - 10.1097/MAO.0000000000001057
DO - 10.1097/MAO.0000000000001057
M3 - Article
C2 - 27203843
AN - SCOPUS:84969835341
SN - 1531-7129
VL - 37
SP - 967
EP - 972
JO - Otology and Neurotology
JF - Otology and Neurotology
IS - 7
ER -