TY - JOUR
T1 - Prevalence of atrial fibrillation and association with clinical, sociocultural, and ancestral correlates among Hispanic/Latinos
T2 - The Hispanic Community Health Study/Study of Latinos
AU - Linares, Jered D.
AU - Jackson, Larry R.
AU - Dawood, Farah Z.
AU - Swett, Katrina
AU - Benjamin, Emelia J.
AU - Schneiderman, Neil
AU - Soliman, Elsayed Z.
AU - Cai, Jianwen
AU - Alonso, Alvaro
AU - Wassertheil-Smoller, Sylvia
AU - Talavera, Gregory A.
AU - Daubert, James P.
AU - Daviglus, Martha L.
AU - Rodriguez, Carlos J.
N1 - Funding Information:
The Hispanic Community Health Study/Study of Latinos was supported by contracts from the National Heart, Lung, and Blood Institute to the University of North Carolina (grant no. N01-HC65233), the University of Miami (grant no. N01-HC65234), the Albert Einstein College of Medicine (grant no. N01-HC65235), Northwestern University (grant no. N01-HC65236), and San Diego State University (grant no. N01-HC65237).This study was partially supported by the National Institutes of Health/National Heart, Lung, and Blood Institute (grant nos. R01 HL104199 [principal investigator: Dr Rodriguez] and T32 HL125294 [principal investigator: Dr Daviglus]). Additional funding was provided by the American Heart Association (grant no. 16EIA26410001, to Dr Alonso). We thank the staff and participants of the Hispanic Community Health Study/Study of Latinos for their important contributions.
Publisher Copyright:
© 2018 Heart Rhythm Society
PY - 2019/5
Y1 - 2019/5
N2 - Background: Hispanics/Latinos represent the largest ethnic minority group in the United States. Atrial fibrillation (AF) is the most common cardiac arrhythmia in the United States. Objective: The purpose of this study was to provide data on the prevalence of AF and its correlates in a representative Hispanic/Latino population–based sample inclusive of all background groups. Methods: Hispanic Community Health Study/Study of Latinos participants (n=16,415; 60% women; 59% age >45 years) were enrolled between March 2008 and June 2011, representing individuals of Cuban, Dominican, Mexican, Puerto Rican, Central American, and South American heritage. AF was defined by the 12-lead electrocardiogram and/or participant self-report of a physician diagnosis. Hispanic background–specific AF prevalence rates were determined. Weighted sequential logistic regression models were adjusted for demographic factors (age and sex) and clinical variables (diabetes, hypertension, body mass index, tobacco use, and estimated glomerular filtration rate). Results: The overall weighted prevalence of AF was 1.0% (n=162), with the highest prevalence in Hispanics of Dominican and Puerto Rican backgrounds (1.9% and 2.5% respectively) and the lowest in those of Mexican background (0.3%). Diabetes, hypertension, renal disease, left ventricular hypertrophy determined by the electrocardiogram, alcohol use, and English language preference (greater acculturation) (P <.01 for all) were significantly associated with higher AF prevalence. Multivariate analysis by Hispanic/Latino background group showed that Hispanics of Dominican and Puerto Rican backgrounds were at a 3- to 6-fold higher risk of AF than their Mexican counterparts. Conclusion: In a diverse representative population of Hispanics/Latinos, overall AF prevalence was low and varied significantly across Hispanic/Latino background groups independent of clinical or demographic factors.
AB - Background: Hispanics/Latinos represent the largest ethnic minority group in the United States. Atrial fibrillation (AF) is the most common cardiac arrhythmia in the United States. Objective: The purpose of this study was to provide data on the prevalence of AF and its correlates in a representative Hispanic/Latino population–based sample inclusive of all background groups. Methods: Hispanic Community Health Study/Study of Latinos participants (n=16,415; 60% women; 59% age >45 years) were enrolled between March 2008 and June 2011, representing individuals of Cuban, Dominican, Mexican, Puerto Rican, Central American, and South American heritage. AF was defined by the 12-lead electrocardiogram and/or participant self-report of a physician diagnosis. Hispanic background–specific AF prevalence rates were determined. Weighted sequential logistic regression models were adjusted for demographic factors (age and sex) and clinical variables (diabetes, hypertension, body mass index, tobacco use, and estimated glomerular filtration rate). Results: The overall weighted prevalence of AF was 1.0% (n=162), with the highest prevalence in Hispanics of Dominican and Puerto Rican backgrounds (1.9% and 2.5% respectively) and the lowest in those of Mexican background (0.3%). Diabetes, hypertension, renal disease, left ventricular hypertrophy determined by the electrocardiogram, alcohol use, and English language preference (greater acculturation) (P <.01 for all) were significantly associated with higher AF prevalence. Multivariate analysis by Hispanic/Latino background group showed that Hispanics of Dominican and Puerto Rican backgrounds were at a 3- to 6-fold higher risk of AF than their Mexican counterparts. Conclusion: In a diverse representative population of Hispanics/Latinos, overall AF prevalence was low and varied significantly across Hispanic/Latino background groups independent of clinical or demographic factors.
KW - Atrial fibrillation
KW - Clinical correlates
KW - Epidemiology
KW - Hispanics
KW - Latinos
UR - http://www.scopus.com/inward/record.url?scp=85064328793&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85064328793&partnerID=8YFLogxK
U2 - 10.1016/j.hrthm.2018.11.033
DO - 10.1016/j.hrthm.2018.11.033
M3 - Article
C2 - 31036248
AN - SCOPUS:85064328793
VL - 16
SP - 686
EP - 693
JO - Heart Rhythm
JF - Heart Rhythm
SN - 1547-5271
IS - 5
ER -
