Prevalence and factors associated with cognitive deficit in women with gynecologic malignancies

Anne R. Van Arsdale, Debra Rosenbaum, Gurpreet Kaur, Priya Pinto, Dennis Yi-Shin Kuo, Ruben Barrera, Gary L. Goldberg, Nicole S. Nevadunsky

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Objective: Cognitive impairment has implications in counseling, treatment, and survivorship for women with gynecologic malignancies. The purpose of our study was to evaluate the prevalence and risk factors associated with cognition in women with gynecologic malignancies. Methods: After Institutional Review Board approval, 165 women at an urban ambulatory gynecologic oncology facility were queried using a Montreal Cognitive Assessment (MoCA), Wong-Baker pain scale, neuropathy scale, Patient Health Questionnaire 9 (PHQ-9) Depression Scale, and Generalized Anxiety Disorder Scale (GAD 7). Univariate and multivariate analyses were utilized to evaluate the association of cognitive deficit with age, education, race/ethnicity, disease site, stage, treatment, pain, neuropathy, anxiety, and depression. Results: The mean MoCA score for the entire cohort was 24.1 (range 13-30.) 24% of patients had MoCA scores less than 22. Low scores (

Original languageEnglish (US)
JournalGynecologic Oncology
DOIs
StateAccepted/In press - Oct 19 2015

Keywords

  • Anxiety
  • Cognition
  • Depression
  • Gynecologic malignancies
  • Pain
  • Quality of life

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology

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