Prevalence and correlates of CKD in hispanics/latinos in the United States

Ana C. Ricardo, Michael F. Flessner, John H. Eckfeldt, Paul W. Eggers, Nora Franceschini, Alan S. Go, Nathan M. Gotman, Holly J. Kramer, John W. Kusek, Laura R. Loehr, Michal L. Melamed, Carmen A. Peralta, Leopoldo Raij, Sylvia E. Rosas, Gregory A. Talavera, James P. Lash

Research output: Contribution to journalArticle

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Abstract

Background and objectives The prevalence of ESRD among Hispanics/Latinos is 2-fold higher than in non-Hispanic whites. However, little is known about the prevalence of earlier stages of CKD among Hispanics/Latinos. This study estimated the prevalence of CKD in US Hispanics/Latinos. Design, setting, participants, & measurements This was a cross-sectional study of 15,161 US Hispanic/Latino adults of Cuban, Dominican, Mexican, Puerto Rican, Central American, and South American backgrounds enrolled in the multicenter, prospective, population-based Hispanic Community Health Study/Study of Latinos (HCHS/SOL). In addition, the prevalence of CKD in Hispanics/Latinos was compared with other racial/ethnic groups in the 2007–2010 National Health and Nutrition Examination Survey (NHANES). Prevalent CKD was defined as an eGFR 2 (estimated with the 2012 Chronic Kidney Disease Epidemiology Collaboration eGFR creatinine-cystatin C equation) or albuminuria based on sex-specific cut points determined at a single point in time. Results The overall prevalence of CKD among Hispanics/Latinos was 13.7%. Among women, the prevalence of CKD was 13.0%, and it was lowest in persons with South American background (7.4%) and highest (16.6%) in persons with Puerto Rican background. In men, the prevalence of CKD was 15.3%, and it was lowest (11.2%) in persons with South American background and highest in those who identified their Hispanic background as “other” (16.0%). The overall prevalence of CKD was similar in HCHS/SOL compared with non-Hispanic whites in NHANES. However, prevalence was higher in HCHS/SOL men and lower in HCHS/SOL women versus NHANES non-Hispanic whites. Low income, diabetes mellitus, hypertension, and cardiovascular disease were each significantly associated with higher risk of CKD. Conclusions Among US Hispanic/Latino adults, there was significant variation in CKD prevalence among Hispanic/Latino background groups, and CKD was associated with established cardiovascular risk factors.

Original languageEnglish (US)
Pages (from-to)1757-1766
Number of pages10
JournalClinical Journal of the American Society of Nephrology
Volume10
Issue number10
DOIs
StatePublished - Oct 7 2015

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Hispanic Americans
Nutrition Surveys
Health
Cross-Sectional Studies
Cystatin C

ASJC Scopus subject areas

  • Nephrology
  • Transplantation
  • Epidemiology
  • Critical Care and Intensive Care Medicine

Cite this

Ricardo, A. C., Flessner, M. F., Eckfeldt, J. H., Eggers, P. W., Franceschini, N., Go, A. S., ... Lash, J. P. (2015). Prevalence and correlates of CKD in hispanics/latinos in the United States. Clinical Journal of the American Society of Nephrology, 10(10), 1757-1766. https://doi.org/10.2215/CJN.02020215

Prevalence and correlates of CKD in hispanics/latinos in the United States. / Ricardo, Ana C.; Flessner, Michael F.; Eckfeldt, John H.; Eggers, Paul W.; Franceschini, Nora; Go, Alan S.; Gotman, Nathan M.; Kramer, Holly J.; Kusek, John W.; Loehr, Laura R.; Melamed, Michal L.; Peralta, Carmen A.; Raij, Leopoldo; Rosas, Sylvia E.; Talavera, Gregory A.; Lash, James P.

In: Clinical Journal of the American Society of Nephrology, Vol. 10, No. 10, 07.10.2015, p. 1757-1766.

Research output: Contribution to journalArticle

Ricardo, AC, Flessner, MF, Eckfeldt, JH, Eggers, PW, Franceschini, N, Go, AS, Gotman, NM, Kramer, HJ, Kusek, JW, Loehr, LR, Melamed, ML, Peralta, CA, Raij, L, Rosas, SE, Talavera, GA & Lash, JP 2015, 'Prevalence and correlates of CKD in hispanics/latinos in the United States', Clinical Journal of the American Society of Nephrology, vol. 10, no. 10, pp. 1757-1766. https://doi.org/10.2215/CJN.02020215
Ricardo AC, Flessner MF, Eckfeldt JH, Eggers PW, Franceschini N, Go AS et al. Prevalence and correlates of CKD in hispanics/latinos in the United States. Clinical Journal of the American Society of Nephrology. 2015 Oct 7;10(10):1757-1766. https://doi.org/10.2215/CJN.02020215
Ricardo, Ana C. ; Flessner, Michael F. ; Eckfeldt, John H. ; Eggers, Paul W. ; Franceschini, Nora ; Go, Alan S. ; Gotman, Nathan M. ; Kramer, Holly J. ; Kusek, John W. ; Loehr, Laura R. ; Melamed, Michal L. ; Peralta, Carmen A. ; Raij, Leopoldo ; Rosas, Sylvia E. ; Talavera, Gregory A. ; Lash, James P. / Prevalence and correlates of CKD in hispanics/latinos in the United States. In: Clinical Journal of the American Society of Nephrology. 2015 ; Vol. 10, No. 10. pp. 1757-1766.
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abstract = "Background and objectives The prevalence of ESRD among Hispanics/Latinos is 2-fold higher than in non-Hispanic whites. However, little is known about the prevalence of earlier stages of CKD among Hispanics/Latinos. This study estimated the prevalence of CKD in US Hispanics/Latinos. Design, setting, participants, & measurements This was a cross-sectional study of 15,161 US Hispanic/Latino adults of Cuban, Dominican, Mexican, Puerto Rican, Central American, and South American backgrounds enrolled in the multicenter, prospective, population-based Hispanic Community Health Study/Study of Latinos (HCHS/SOL). In addition, the prevalence of CKD in Hispanics/Latinos was compared with other racial/ethnic groups in the 2007–2010 National Health and Nutrition Examination Survey (NHANES). Prevalent CKD was defined as an eGFR 2 (estimated with the 2012 Chronic Kidney Disease Epidemiology Collaboration eGFR creatinine-cystatin C equation) or albuminuria based on sex-specific cut points determined at a single point in time. Results The overall prevalence of CKD among Hispanics/Latinos was 13.7{\%}. Among women, the prevalence of CKD was 13.0{\%}, and it was lowest in persons with South American background (7.4{\%}) and highest (16.6{\%}) in persons with Puerto Rican background. In men, the prevalence of CKD was 15.3{\%}, and it was lowest (11.2{\%}) in persons with South American background and highest in those who identified their Hispanic background as “other” (16.0{\%}). The overall prevalence of CKD was similar in HCHS/SOL compared with non-Hispanic whites in NHANES. However, prevalence was higher in HCHS/SOL men and lower in HCHS/SOL women versus NHANES non-Hispanic whites. Low income, diabetes mellitus, hypertension, and cardiovascular disease were each significantly associated with higher risk of CKD. Conclusions Among US Hispanic/Latino adults, there was significant variation in CKD prevalence among Hispanic/Latino background groups, and CKD was associated with established cardiovascular risk factors.",
author = "Ricardo, {Ana C.} and Flessner, {Michael F.} and Eckfeldt, {John H.} and Eggers, {Paul W.} and Nora Franceschini and Go, {Alan S.} and Gotman, {Nathan M.} and Kramer, {Holly J.} and Kusek, {John W.} and Loehr, {Laura R.} and Melamed, {Michal L.} and Peralta, {Carmen A.} and Leopoldo Raij and Rosas, {Sylvia E.} and Talavera, {Gregory A.} and Lash, {James P.}",
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T1 - Prevalence and correlates of CKD in hispanics/latinos in the United States

AU - Ricardo, Ana C.

AU - Flessner, Michael F.

AU - Eckfeldt, John H.

AU - Eggers, Paul W.

AU - Franceschini, Nora

AU - Go, Alan S.

AU - Gotman, Nathan M.

AU - Kramer, Holly J.

AU - Kusek, John W.

AU - Loehr, Laura R.

AU - Melamed, Michal L.

AU - Peralta, Carmen A.

AU - Raij, Leopoldo

AU - Rosas, Sylvia E.

AU - Talavera, Gregory A.

AU - Lash, James P.

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N2 - Background and objectives The prevalence of ESRD among Hispanics/Latinos is 2-fold higher than in non-Hispanic whites. However, little is known about the prevalence of earlier stages of CKD among Hispanics/Latinos. This study estimated the prevalence of CKD in US Hispanics/Latinos. Design, setting, participants, & measurements This was a cross-sectional study of 15,161 US Hispanic/Latino adults of Cuban, Dominican, Mexican, Puerto Rican, Central American, and South American backgrounds enrolled in the multicenter, prospective, population-based Hispanic Community Health Study/Study of Latinos (HCHS/SOL). In addition, the prevalence of CKD in Hispanics/Latinos was compared with other racial/ethnic groups in the 2007–2010 National Health and Nutrition Examination Survey (NHANES). Prevalent CKD was defined as an eGFR 2 (estimated with the 2012 Chronic Kidney Disease Epidemiology Collaboration eGFR creatinine-cystatin C equation) or albuminuria based on sex-specific cut points determined at a single point in time. Results The overall prevalence of CKD among Hispanics/Latinos was 13.7%. Among women, the prevalence of CKD was 13.0%, and it was lowest in persons with South American background (7.4%) and highest (16.6%) in persons with Puerto Rican background. In men, the prevalence of CKD was 15.3%, and it was lowest (11.2%) in persons with South American background and highest in those who identified their Hispanic background as “other” (16.0%). The overall prevalence of CKD was similar in HCHS/SOL compared with non-Hispanic whites in NHANES. However, prevalence was higher in HCHS/SOL men and lower in HCHS/SOL women versus NHANES non-Hispanic whites. Low income, diabetes mellitus, hypertension, and cardiovascular disease were each significantly associated with higher risk of CKD. Conclusions Among US Hispanic/Latino adults, there was significant variation in CKD prevalence among Hispanic/Latino background groups, and CKD was associated with established cardiovascular risk factors.

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