Prevalence and characteristics of pseudohypertension in patients with resistant hypertension

Mark Kleman, Susmitha Dhanyamraju, William Difilippo

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Pseudohypertension has been described as a cause of resistant hypertension, due to medial hypertrophy of the artery from atherosclerosis. This phenomenon results in an elevated cuff pressure compared with intra-arterial measurements and is found primarily in populations with advanced age and atherosclerotic disease. The purpose of this review was to investigate the clinical picture and medical outcomes of patients with this phenomenon. We conducted a retrospective chart review between April 2009 and October 2011 of 244 patients seen in our Hypertension clinic. Baseline characteristics and outcomes of pharmacologic and lifestyle modifications were analyzed. There were 17/244 (7%) patients found to have pseudohypertension among patients enrolled. The mean number of antihypertensive medications decreased from 3.7 to 2.7, following a mean of 4.1 visits. All patients had a brachial artery bruit and triphasic blood pressure readings via Doppler. Our findings suggest that elderly patients with concomitant history of atherosclerotic disease, renal insufficiency, and diabetes mellitus have the highest risk of developing pseudohypertension. This condition should be considered in patients with resistant hypertension. Blood pressure measurement with Doppler can be considered as a noninvasive investigation. Recognition of this entity may result in potential cost reduction with fewer medications prescribed.

Original languageEnglish (US)
Pages (from-to)467-470
Number of pages4
JournalJournal of the American Society of Hypertension
Volume7
Issue number6
DOIs
StatePublished - Nov 2013
Externally publishedYes

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Hypertension
Blood Pressure
Brachial Artery
Hypertrophy
Antihypertensive Agents
Renal Insufficiency
Life Style
Reading
Atherosclerosis
Diabetes Mellitus
Arteries
Pressure
Costs and Cost Analysis
Population

Keywords

  • Pseudohypertension
  • resistant hypertension

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Internal Medicine

Cite this

Prevalence and characteristics of pseudohypertension in patients with resistant hypertension. / Kleman, Mark; Dhanyamraju, Susmitha; Difilippo, William.

In: Journal of the American Society of Hypertension, Vol. 7, No. 6, 11.2013, p. 467-470.

Research output: Contribution to journalArticle

Kleman, Mark ; Dhanyamraju, Susmitha ; Difilippo, William. / Prevalence and characteristics of pseudohypertension in patients with resistant hypertension. In: Journal of the American Society of Hypertension. 2013 ; Vol. 7, No. 6. pp. 467-470.
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