Prevalence and characteristics of hepatitis C virus coinfection in a human immunodefidency virus clinical trials group: The Terry Beirn Community Programs for Clinical Research on AIDS

Ellen M. Tedaldi, Katherine Huppler Hullsiek, Carlos D. Malvestutto, Roberto C. Arduino, Evelyn J. Fisher, Paul J. Gaglio, Elizabeth R. Jenny-Avital, Joseph P. McGowan, George Perez

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

The baseline prevalence of hepatitis C virus (HCV) and human immunodeficiency virus (HIV) coinfection among 2705 patients enrolled in HIV clinical trials in the Community Programs for Clinical Research on AIDS (CPCRA) was 16.6%. For men, multivariate logistic regression showed that the baseline prevalence of HIV-HCV coinfection was positively associated with history of injection drug use, older age, antiretroviral therapy naive status, African American or Latino ethnicity, and no history of having sex with men. No association was found with baseline CD4+ cell count or HIV RNA level. The prevalence of HCV coinfection in a diverse HIV clinical trials cohort provides additional information about risk behaviors and demographic factors that can be used in the analysis of clinical and virologic outcomes.

Original languageEnglish (US)
Pages (from-to)1313-1317
Number of pages5
JournalClinical Infectious Diseases
Volume36
Issue number10
DOIs
StatePublished - May 15 2003
Externally publishedYes

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Coinfection
Hepacivirus
Acquired Immunodeficiency Syndrome
Clinical Trials
HIV
Viruses
Research
CD4 Lymphocyte Count
Risk-Taking
Hispanic Americans
African Americans
Logistic Models
Demography
RNA
Injections
Pharmaceutical Preparations
Therapeutics

ASJC Scopus subject areas

  • Immunology

Cite this

Prevalence and characteristics of hepatitis C virus coinfection in a human immunodefidency virus clinical trials group : The Terry Beirn Community Programs for Clinical Research on AIDS. / Tedaldi, Ellen M.; Huppler Hullsiek, Katherine; Malvestutto, Carlos D.; Arduino, Roberto C.; Fisher, Evelyn J.; Gaglio, Paul J.; Jenny-Avital, Elizabeth R.; McGowan, Joseph P.; Perez, George.

In: Clinical Infectious Diseases, Vol. 36, No. 10, 15.05.2003, p. 1313-1317.

Research output: Contribution to journalArticle

Tedaldi, EM, Huppler Hullsiek, K, Malvestutto, CD, Arduino, RC, Fisher, EJ, Gaglio, PJ, Jenny-Avital, ER, McGowan, JP & Perez, G 2003, 'Prevalence and characteristics of hepatitis C virus coinfection in a human immunodefidency virus clinical trials group: The Terry Beirn Community Programs for Clinical Research on AIDS', Clinical Infectious Diseases, vol. 36, no. 10, pp. 1313-1317. https://doi.org/10.1086/374841
Tedaldi, Ellen M. ; Huppler Hullsiek, Katherine ; Malvestutto, Carlos D. ; Arduino, Roberto C. ; Fisher, Evelyn J. ; Gaglio, Paul J. ; Jenny-Avital, Elizabeth R. ; McGowan, Joseph P. ; Perez, George. / Prevalence and characteristics of hepatitis C virus coinfection in a human immunodefidency virus clinical trials group : The Terry Beirn Community Programs for Clinical Research on AIDS. In: Clinical Infectious Diseases. 2003 ; Vol. 36, No. 10. pp. 1313-1317.
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