Preparation of Polyfunctional Heterocycles Using Highly Functionalized Aminated Arylmagnesium Reagents as Versatile Scaffolds

David M. Lindsay, Wolfgang Dohle, Anne Eeg Jensen, Felix Kopp, Paul Knochel

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

(Equation Presented) Functionalized Grignard reagents, derived from readily available o-iodoaniline derivatives and obtained via a straightforward iodine-magnesium exchange, can be used to prepare a wide range of polyfunctional indoles, quinolines, and quinazolinones.

Original languageEnglish (US)
Pages (from-to)1819-1822
Number of pages4
JournalOrganic Letters
Volume4
Issue number11
DOIs
StatePublished - May 30 2002
Externally publishedYes

Fingerprint

Quinazolinones
Quinolines
Indoles
quinoline
indoles
Scaffolds
Iodine
Magnesium
iodine
reagents
magnesium
Derivatives
preparation
3-iodoaniline

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Preparation of Polyfunctional Heterocycles Using Highly Functionalized Aminated Arylmagnesium Reagents as Versatile Scaffolds. / Lindsay, David M.; Dohle, Wolfgang; Jensen, Anne Eeg; Kopp, Felix; Knochel, Paul.

In: Organic Letters, Vol. 4, No. 11, 30.05.2002, p. 1819-1822.

Research output: Contribution to journalArticle

Lindsay, David M. ; Dohle, Wolfgang ; Jensen, Anne Eeg ; Kopp, Felix ; Knochel, Paul. / Preparation of Polyfunctional Heterocycles Using Highly Functionalized Aminated Arylmagnesium Reagents as Versatile Scaffolds. In: Organic Letters. 2002 ; Vol. 4, No. 11. pp. 1819-1822.
@article{54492dba3f904b51b655c00891698553,
title = "Preparation of Polyfunctional Heterocycles Using Highly Functionalized Aminated Arylmagnesium Reagents as Versatile Scaffolds",
abstract = "(Equation Presented) Functionalized Grignard reagents, derived from readily available o-iodoaniline derivatives and obtained via a straightforward iodine-magnesium exchange, can be used to prepare a wide range of polyfunctional indoles, quinolines, and quinazolinones.",
author = "Lindsay, {David M.} and Wolfgang Dohle and Jensen, {Anne Eeg} and Felix Kopp and Paul Knochel",
year = "2002",
month = "5",
day = "30",
doi = "10.1021/ol025597x",
language = "English (US)",
volume = "4",
pages = "1819--1822",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "11",

}

TY - JOUR

T1 - Preparation of Polyfunctional Heterocycles Using Highly Functionalized Aminated Arylmagnesium Reagents as Versatile Scaffolds

AU - Lindsay, David M.

AU - Dohle, Wolfgang

AU - Jensen, Anne Eeg

AU - Kopp, Felix

AU - Knochel, Paul

PY - 2002/5/30

Y1 - 2002/5/30

N2 - (Equation Presented) Functionalized Grignard reagents, derived from readily available o-iodoaniline derivatives and obtained via a straightforward iodine-magnesium exchange, can be used to prepare a wide range of polyfunctional indoles, quinolines, and quinazolinones.

AB - (Equation Presented) Functionalized Grignard reagents, derived from readily available o-iodoaniline derivatives and obtained via a straightforward iodine-magnesium exchange, can be used to prepare a wide range of polyfunctional indoles, quinolines, and quinazolinones.

UR - http://www.scopus.com/inward/record.url?scp=0001651959&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0001651959&partnerID=8YFLogxK

U2 - 10.1021/ol025597x

DO - 10.1021/ol025597x

M3 - Article

VL - 4

SP - 1819

EP - 1822

JO - Organic Letters

JF - Organic Letters

SN - 1523-7060

IS - 11

ER -