Preoperative thyroid ultrasound is indicated in patients undergoing par-athyroidectomy for primary hyperparathyroidism

Cletus A. Arciero, S. Zita Shiue, Jeremy D. Gates, George E. Peoples, Alan P B Dackiw, Ralph P. Tufano, Steven K. Libutti, Martha A. Zeiger, Alexander Stojadinovic

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Background: Primary hyperaparathyroidism (pHPT) is often accompanied by underlying thyroid pathology that can confound preoperative parathyroid localization studies and com-plicate intra-operative decision making. The aim of this study was to examine the utility of preoperative thyroid ultrasonography (US) in patients prior to undergoing parathyroidec-tomy for pHPT. Methods: An Institutional Review Board approved prospective study was undertaken from January 2005 through July 2008. All patients with pHPT meeting inclusion criteria (n=94) underwent preoperative thyroid ultrasound in addition to standard 99mTc-sestamibi scintig-raphy for parathyroid localization. Demographics, operative management and final pathology were examined in all cases. Results: Fifty-four of the 94 patients (57%) were noted to have a thyroid nodule on pre-operative US, of which 30 (56%) underwent further examination with fine needle aspiration biopsy. Alteration of the operative plan attributable to underlying thyroid pathology occurred in 16 patients (17%), with patients undergoing either total thyroidectomy (n=9) or thyroid lobectomy (n=7). Thyroid cancer was noted in 33% of patients undergoing thyroid resection, and 6% of all patients with HPT. Conclusions: The routine utilization of preoperative thyroid ultrasound in patients prior to undergoing parathyroid surgery for pHPT is indicated. The added information from this non-invasive modality facilitates timely management of co-incidental, and sometimes malig-nant, thyroid pathology.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalJournal of Cancer
Volume3
Issue number1
DOIs
StatePublished - 2012

Fingerprint

Primary Hyperparathyroidism
Thyroid Gland
Pathology
Ultrasonography
Technetium Tc 99m Sestamibi
Thyroid Nodule
Research Ethics Committees
Thyroidectomy
Fine Needle Biopsy
Thyroid Neoplasms
Decision Making
Demography
Prospective Studies

Keywords

  • Hyperparathyroidism
  • Surgery
  • Thyroid
  • Thyroid cancer
  • Ultrasound

ASJC Scopus subject areas

  • Oncology

Cite this

Arciero, C. A., Shiue, S. Z., Gates, J. D., Peoples, G. E., Dackiw, A. P. B., Tufano, R. P., ... Stojadinovic, A. (2012). Preoperative thyroid ultrasound is indicated in patients undergoing par-athyroidectomy for primary hyperparathyroidism. Journal of Cancer, 3(1), 1-6. https://doi.org/10.7150/jca.3.1

Preoperative thyroid ultrasound is indicated in patients undergoing par-athyroidectomy for primary hyperparathyroidism. / Arciero, Cletus A.; Shiue, S. Zita; Gates, Jeremy D.; Peoples, George E.; Dackiw, Alan P B; Tufano, Ralph P.; Libutti, Steven K.; Zeiger, Martha A.; Stojadinovic, Alexander.

In: Journal of Cancer, Vol. 3, No. 1, 2012, p. 1-6.

Research output: Contribution to journalArticle

Arciero, CA, Shiue, SZ, Gates, JD, Peoples, GE, Dackiw, APB, Tufano, RP, Libutti, SK, Zeiger, MA & Stojadinovic, A 2012, 'Preoperative thyroid ultrasound is indicated in patients undergoing par-athyroidectomy for primary hyperparathyroidism', Journal of Cancer, vol. 3, no. 1, pp. 1-6. https://doi.org/10.7150/jca.3.1
Arciero, Cletus A. ; Shiue, S. Zita ; Gates, Jeremy D. ; Peoples, George E. ; Dackiw, Alan P B ; Tufano, Ralph P. ; Libutti, Steven K. ; Zeiger, Martha A. ; Stojadinovic, Alexander. / Preoperative thyroid ultrasound is indicated in patients undergoing par-athyroidectomy for primary hyperparathyroidism. In: Journal of Cancer. 2012 ; Vol. 3, No. 1. pp. 1-6.
@article{1e2805ee5dfc453086d6f796d292609a,
title = "Preoperative thyroid ultrasound is indicated in patients undergoing par-athyroidectomy for primary hyperparathyroidism",
abstract = "Background: Primary hyperaparathyroidism (pHPT) is often accompanied by underlying thyroid pathology that can confound preoperative parathyroid localization studies and com-plicate intra-operative decision making. The aim of this study was to examine the utility of preoperative thyroid ultrasonography (US) in patients prior to undergoing parathyroidec-tomy for pHPT. Methods: An Institutional Review Board approved prospective study was undertaken from January 2005 through July 2008. All patients with pHPT meeting inclusion criteria (n=94) underwent preoperative thyroid ultrasound in addition to standard 99mTc-sestamibi scintig-raphy for parathyroid localization. Demographics, operative management and final pathology were examined in all cases. Results: Fifty-four of the 94 patients (57{\%}) were noted to have a thyroid nodule on pre-operative US, of which 30 (56{\%}) underwent further examination with fine needle aspiration biopsy. Alteration of the operative plan attributable to underlying thyroid pathology occurred in 16 patients (17{\%}), with patients undergoing either total thyroidectomy (n=9) or thyroid lobectomy (n=7). Thyroid cancer was noted in 33{\%} of patients undergoing thyroid resection, and 6{\%} of all patients with HPT. Conclusions: The routine utilization of preoperative thyroid ultrasound in patients prior to undergoing parathyroid surgery for pHPT is indicated. The added information from this non-invasive modality facilitates timely management of co-incidental, and sometimes malig-nant, thyroid pathology.",
keywords = "Hyperparathyroidism, Surgery, Thyroid, Thyroid cancer, Ultrasound",
author = "Arciero, {Cletus A.} and Shiue, {S. Zita} and Gates, {Jeremy D.} and Peoples, {George E.} and Dackiw, {Alan P B} and Tufano, {Ralph P.} and Libutti, {Steven K.} and Zeiger, {Martha A.} and Alexander Stojadinovic",
year = "2012",
doi = "10.7150/jca.3.1",
language = "English (US)",
volume = "3",
pages = "1--6",
journal = "Journal of Cancer",
issn = "1837-9664",
publisher = "Ivyspring International Publisher",
number = "1",

}

TY - JOUR

T1 - Preoperative thyroid ultrasound is indicated in patients undergoing par-athyroidectomy for primary hyperparathyroidism

AU - Arciero, Cletus A.

AU - Shiue, S. Zita

AU - Gates, Jeremy D.

AU - Peoples, George E.

AU - Dackiw, Alan P B

AU - Tufano, Ralph P.

AU - Libutti, Steven K.

AU - Zeiger, Martha A.

AU - Stojadinovic, Alexander

PY - 2012

Y1 - 2012

N2 - Background: Primary hyperaparathyroidism (pHPT) is often accompanied by underlying thyroid pathology that can confound preoperative parathyroid localization studies and com-plicate intra-operative decision making. The aim of this study was to examine the utility of preoperative thyroid ultrasonography (US) in patients prior to undergoing parathyroidec-tomy for pHPT. Methods: An Institutional Review Board approved prospective study was undertaken from January 2005 through July 2008. All patients with pHPT meeting inclusion criteria (n=94) underwent preoperative thyroid ultrasound in addition to standard 99mTc-sestamibi scintig-raphy for parathyroid localization. Demographics, operative management and final pathology were examined in all cases. Results: Fifty-four of the 94 patients (57%) were noted to have a thyroid nodule on pre-operative US, of which 30 (56%) underwent further examination with fine needle aspiration biopsy. Alteration of the operative plan attributable to underlying thyroid pathology occurred in 16 patients (17%), with patients undergoing either total thyroidectomy (n=9) or thyroid lobectomy (n=7). Thyroid cancer was noted in 33% of patients undergoing thyroid resection, and 6% of all patients with HPT. Conclusions: The routine utilization of preoperative thyroid ultrasound in patients prior to undergoing parathyroid surgery for pHPT is indicated. The added information from this non-invasive modality facilitates timely management of co-incidental, and sometimes malig-nant, thyroid pathology.

AB - Background: Primary hyperaparathyroidism (pHPT) is often accompanied by underlying thyroid pathology that can confound preoperative parathyroid localization studies and com-plicate intra-operative decision making. The aim of this study was to examine the utility of preoperative thyroid ultrasonography (US) in patients prior to undergoing parathyroidec-tomy for pHPT. Methods: An Institutional Review Board approved prospective study was undertaken from January 2005 through July 2008. All patients with pHPT meeting inclusion criteria (n=94) underwent preoperative thyroid ultrasound in addition to standard 99mTc-sestamibi scintig-raphy for parathyroid localization. Demographics, operative management and final pathology were examined in all cases. Results: Fifty-four of the 94 patients (57%) were noted to have a thyroid nodule on pre-operative US, of which 30 (56%) underwent further examination with fine needle aspiration biopsy. Alteration of the operative plan attributable to underlying thyroid pathology occurred in 16 patients (17%), with patients undergoing either total thyroidectomy (n=9) or thyroid lobectomy (n=7). Thyroid cancer was noted in 33% of patients undergoing thyroid resection, and 6% of all patients with HPT. Conclusions: The routine utilization of preoperative thyroid ultrasound in patients prior to undergoing parathyroid surgery for pHPT is indicated. The added information from this non-invasive modality facilitates timely management of co-incidental, and sometimes malig-nant, thyroid pathology.

KW - Hyperparathyroidism

KW - Surgery

KW - Thyroid

KW - Thyroid cancer

KW - Ultrasound

UR - http://www.scopus.com/inward/record.url?scp=84879646805&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879646805&partnerID=8YFLogxK

U2 - 10.7150/jca.3.1

DO - 10.7150/jca.3.1

M3 - Article

VL - 3

SP - 1

EP - 6

JO - Journal of Cancer

JF - Journal of Cancer

SN - 1837-9664

IS - 1

ER -