Preoperative Heart Failure Treatment Prevents Postoperative Cardiac Complications in Patients with Lower Risk: A Retrospective Cohort Study

Denys Shay, Pauline Y. Ng, David M. Dudzinski, Stephanie D. Grabitz, John D. Mitchell, Xinling Xu, Timothy T. Houle, Deepak L. Bhatt, Matthias Eikermann

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Objective: The objective of this study was to identify undertreated subgroups of patients with heart failure who would benefit from better perioperative optimization. Summary of Background Data: Patients with heart failure have increased risks of postoperative cardiac complications after noncardiac surgery. Methods: In this analysis of hospital registry data of 130,677 patients undergoing noncardiac surgery, the exposure was preoperative history of heart failure. The outcome, cardiac complications, was defined as a composite of myocardial infarction, cardiac arrest, acute heart failure, and mortality within 30 postoperative days. Results: History of heart failure (n = 10,256; 7.9%) was associated with increased risk of cardiac complications [8.1% vs 1.1%; adjusted odds ratio, 2.28 (95% CI, 2.02-2.56); P < 0.001). Patients with heart failure and who carried a lower risk profile had increased risks of postoperative cardiac complications secondary to heart failure [adjusted absolute risk difference, 1.7% (95% CI, 1.4%-2.0%, lower risk); P < 0.001 vs 0.5% (95% CI, -0.6% to 1.6%, higher risk); P = 0.38]. Patients with heart failure and lower risk received a lower level of health care utilization preoperatively, and less frequently received anti-heart failure medications (59% vs 72% and 61% vs 82%; both P < 0.001). These preventive therapies significantly decreased the risk of cardiac complications in patients with heart failure. Conclusions: In patients with heart failure who have a lower preoperative risk profile, clinicians often make insufficient attempts to optimize their clinical condition preoperatively. Preoperative preventive treatment reduces the risk of postoperative cardiac complications in these lower-risk patients with heart failure.

Original languageEnglish (US)
Pages (from-to)E33-E39
JournalAnnals of surgery
Volume277
Issue number1
DOIs
StatePublished - Jan 1 2023

Keywords

  • cardiovascular complications
  • heart failure
  • perioperative treatment

ASJC Scopus subject areas

  • Surgery

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