@article{d05ead464fcd4d9a942e463d0542045c,
title = "Prenatal diagnosis and carrier detection of genetic diseases by analysis of deoxyribonucleic acid",
author = "Harry Ostrer and Hejtmancik, {J. Fielding}",
note = "Funding Information: Recent progress in molecular genetics has resulted in the development of tests for prenatal and presymptomatic diagnosis and for carrier detection of many inherited diseases. Because of the frequency of some of these conditions, physicians are likely to have requests for diagnostic services. Here we discuss the nature of the tests that are available, the type of information they provide, and suggestions designed to help pediatricians interpret the results for the family. We supplement previous articles in The Journal that have reviewed some of the basic techniques of the molecular geneticist ~ and applications of restriction, endonucleases in the diagnosis of genetic disease. 2 Supported in part by grants from the March of Dimes Birth Defects Foundation; the American Cancer Society, Florida Division; and the State of Florida Department of Health and Rehabilitative Services. Reprint requests: Harry Ostrer, MD, Department of Pediatrics, Box J-296, J. Hillis Miller Health Center, UniverSity of Florida, Gainesville, FL 32610-0296. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",
year = "1988",
month = may,
doi = "10.1016/S0022-3476(88)80682-6",
language = "English (US)",
volume = "112",
pages = "679--687",
journal = "Journal of Pediatrics",
issn = "0022-3476",
publisher = "Mosby Inc.",
number = "5",
}