Pregnancy in women with perinatally acquired HIV-infection

Outcomes and challenges

Usha K. Phillips, Michael G. Rosenberg, Joanna Dobroszycki, Mindy Joy Katz, Jorge Sansary, Mindy A. Golatt, Andrew A. Wiznia, Jacobo Abadi

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

This is a retrospective comparison of pregnant women with perinatally acquired HIV-infection (PAH) with a cohort of pregnant women with behaviorally acquired HIV-infection (BAH). PAH cases (11 women) included all pregnant adolescents followed at our HIV clinic from January 2000 to January 2009. BAH cases (27 women) were randomly selected from all deliveries within the study period at the same institution. Demographics, mode of delivery, CD4+ counts, and viral loads (VLs) before, during, and six months postpartum, as well as neonatal outcomes, were reviewed. CD4 counts were significantly lower in the PAH group. VLs were statistically higher in the PAH group. VLs were undetectable at delivery in 60% of the PAH group compared with 88% of the BAH group. No cases of vertical transmission occurred. PAH women may be at a higher risk for HIV-related disease progression. This may increase vertical transmission risks. Further studies and interventions with this growing population are warranted.

Original languageEnglish (US)
Pages (from-to)1076-1082
Number of pages7
JournalAIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV
Volume23
Issue number9
DOIs
StatePublished - Sep 2011

Fingerprint

HIV Infections
pregnancy
Pregnancy
Viral Load
Group
CD4 Lymphocyte Count
Pregnant Women
HIV
adolescent
Disease
Postpartum Period
Disease Progression
Demography
Population

Keywords

  • adolescent
  • behaviorally acquired HIV-infection
  • pregnancy
  • vertical HIV-infection
  • young adult

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health(social science)
  • Social Psychology

Cite this

Pregnancy in women with perinatally acquired HIV-infection : Outcomes and challenges. / Phillips, Usha K.; Rosenberg, Michael G.; Dobroszycki, Joanna; Katz, Mindy Joy; Sansary, Jorge; Golatt, Mindy A.; Wiznia, Andrew A.; Abadi, Jacobo.

In: AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV, Vol. 23, No. 9, 09.2011, p. 1076-1082.

Research output: Contribution to journalArticle

Phillips, UK, Rosenberg, MG, Dobroszycki, J, Katz, MJ, Sansary, J, Golatt, MA, Wiznia, AA & Abadi, J 2011, 'Pregnancy in women with perinatally acquired HIV-infection: Outcomes and challenges', AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV, vol. 23, no. 9, pp. 1076-1082. https://doi.org/10.1080/09540121.2011.554643
Phillips, Usha K. ; Rosenberg, Michael G. ; Dobroszycki, Joanna ; Katz, Mindy Joy ; Sansary, Jorge ; Golatt, Mindy A. ; Wiznia, Andrew A. ; Abadi, Jacobo. / Pregnancy in women with perinatally acquired HIV-infection : Outcomes and challenges. In: AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV. 2011 ; Vol. 23, No. 9. pp. 1076-1082.
@article{044aba80e51449bf8681132e5102e4de,
title = "Pregnancy in women with perinatally acquired HIV-infection: Outcomes and challenges",
abstract = "This is a retrospective comparison of pregnant women with perinatally acquired HIV-infection (PAH) with a cohort of pregnant women with behaviorally acquired HIV-infection (BAH). PAH cases (11 women) included all pregnant adolescents followed at our HIV clinic from January 2000 to January 2009. BAH cases (27 women) were randomly selected from all deliveries within the study period at the same institution. Demographics, mode of delivery, CD4+ counts, and viral loads (VLs) before, during, and six months postpartum, as well as neonatal outcomes, were reviewed. CD4 counts were significantly lower in the PAH group. VLs were statistically higher in the PAH group. VLs were undetectable at delivery in 60{\%} of the PAH group compared with 88{\%} of the BAH group. No cases of vertical transmission occurred. PAH women may be at a higher risk for HIV-related disease progression. This may increase vertical transmission risks. Further studies and interventions with this growing population are warranted.",
keywords = "adolescent, behaviorally acquired HIV-infection, pregnancy, vertical HIV-infection, young adult",
author = "Phillips, {Usha K.} and Rosenberg, {Michael G.} and Joanna Dobroszycki and Katz, {Mindy Joy} and Jorge Sansary and Golatt, {Mindy A.} and Wiznia, {Andrew A.} and Jacobo Abadi",
year = "2011",
month = "9",
doi = "10.1080/09540121.2011.554643",
language = "English (US)",
volume = "23",
pages = "1076--1082",
journal = "AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV",
issn = "0954-0121",
publisher = "Routledge",
number = "9",

}

TY - JOUR

T1 - Pregnancy in women with perinatally acquired HIV-infection

T2 - Outcomes and challenges

AU - Phillips, Usha K.

AU - Rosenberg, Michael G.

AU - Dobroszycki, Joanna

AU - Katz, Mindy Joy

AU - Sansary, Jorge

AU - Golatt, Mindy A.

AU - Wiznia, Andrew A.

AU - Abadi, Jacobo

PY - 2011/9

Y1 - 2011/9

N2 - This is a retrospective comparison of pregnant women with perinatally acquired HIV-infection (PAH) with a cohort of pregnant women with behaviorally acquired HIV-infection (BAH). PAH cases (11 women) included all pregnant adolescents followed at our HIV clinic from January 2000 to January 2009. BAH cases (27 women) were randomly selected from all deliveries within the study period at the same institution. Demographics, mode of delivery, CD4+ counts, and viral loads (VLs) before, during, and six months postpartum, as well as neonatal outcomes, were reviewed. CD4 counts were significantly lower in the PAH group. VLs were statistically higher in the PAH group. VLs were undetectable at delivery in 60% of the PAH group compared with 88% of the BAH group. No cases of vertical transmission occurred. PAH women may be at a higher risk for HIV-related disease progression. This may increase vertical transmission risks. Further studies and interventions with this growing population are warranted.

AB - This is a retrospective comparison of pregnant women with perinatally acquired HIV-infection (PAH) with a cohort of pregnant women with behaviorally acquired HIV-infection (BAH). PAH cases (11 women) included all pregnant adolescents followed at our HIV clinic from January 2000 to January 2009. BAH cases (27 women) were randomly selected from all deliveries within the study period at the same institution. Demographics, mode of delivery, CD4+ counts, and viral loads (VLs) before, during, and six months postpartum, as well as neonatal outcomes, were reviewed. CD4 counts were significantly lower in the PAH group. VLs were statistically higher in the PAH group. VLs were undetectable at delivery in 60% of the PAH group compared with 88% of the BAH group. No cases of vertical transmission occurred. PAH women may be at a higher risk for HIV-related disease progression. This may increase vertical transmission risks. Further studies and interventions with this growing population are warranted.

KW - adolescent

KW - behaviorally acquired HIV-infection

KW - pregnancy

KW - vertical HIV-infection

KW - young adult

UR - http://www.scopus.com/inward/record.url?scp=80052136538&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80052136538&partnerID=8YFLogxK

U2 - 10.1080/09540121.2011.554643

DO - 10.1080/09540121.2011.554643

M3 - Article

VL - 23

SP - 1076

EP - 1082

JO - AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV

JF - AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV

SN - 0954-0121

IS - 9

ER -