TY - JOUR
T1 - Prefrontal Coding of Temporally Discounted Values during Intertemporal Choice
AU - Kim, Soyoun
AU - Hwang, Jaewon
AU - Lee, Daeyeol
N1 - Funding Information:
We are grateful to B. Davis and L. Carr for their help with the experiments. This research was supported by a grant from the National Institute of Health (P01 NS048328).
PY - 2008/7/10
Y1 - 2008/7/10
N2 - Reward from a particular action is seldom immediate, and the influence of such delayed outcome on choice decreases with delay. It has been postulated that when faced with immediate and delayed rewards, decision makers choose the option with maximum temporally discounted value. We examined the preference of monkeys for delayed reward in an intertemporal choice task and the neural basis for real-time computation of temporally discounted values in the dorsolateral prefrontal cortex. During this task, the locations of the targets associated with small or large rewards and their corresponding delays were randomly varied. We found that prefrontal neurons often encoded the temporally discounted value of reward expected from a particular option. Furthermore, activity tended to increase when discounted values for targets were presented in the neuron's preferred direction, suggesting that activity related to temporally discounted values in the prefrontal cortex might determine the animal's behavior during intertemporal choice.
AB - Reward from a particular action is seldom immediate, and the influence of such delayed outcome on choice decreases with delay. It has been postulated that when faced with immediate and delayed rewards, decision makers choose the option with maximum temporally discounted value. We examined the preference of monkeys for delayed reward in an intertemporal choice task and the neural basis for real-time computation of temporally discounted values in the dorsolateral prefrontal cortex. During this task, the locations of the targets associated with small or large rewards and their corresponding delays were randomly varied. We found that prefrontal neurons often encoded the temporally discounted value of reward expected from a particular option. Furthermore, activity tended to increase when discounted values for targets were presented in the neuron's preferred direction, suggesting that activity related to temporally discounted values in the prefrontal cortex might determine the animal's behavior during intertemporal choice.
KW - SYSNEURO
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U2 - 10.1016/j.neuron.2008.05.010
DO - 10.1016/j.neuron.2008.05.010
M3 - Article
C2 - 18614037
AN - SCOPUS:46149117259
SN - 0896-6273
VL - 59
SP - 161
EP - 172
JO - Neuron
JF - Neuron
IS - 1
ER -