Predisposing factors and etiologic diagnosis of ulcerative keratitis

Tasanee Sirikul, Tisha Prabriputaloong, Achavee Smathivat, Roy S. Chuck, Anun Vongthongsri

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

PURPOSE: To determine the predisposing factors, demographic characteristics, and etiology of ulcerative keratitis in a referral center in Bangkok, Thailand. METHODS: The medical records of admitted patients with positive-culture ulcerative keratitis were retrospectively reviewed for demographic data, predisposing factors, and microbial culture results. Predisposing factors were compared between bacterial and fungal keratitis. RESULTS: From January 2001 to December 2004, there were 127 positive-culture ulcerative keratitis cases. The most frequent microbiological diagnosis was bacterial keratitis (76 eyes, 60%), followed by fungal (48 eyes, 38%) and Acanthamoeba keratitis (3 eyes, 2%). The most common organisms isolated were Pseudomonas spp. for bacteria and Fusarium spp. for fungus. Compared with bacterial keratitis, fungal keratitis was more likely to be associated with ocular trauma (odds ratio = 11.20; 95% confidence interval, 3.62-34.66) but less likely to be associated with contact lens wear (odds ratio = 0.02; 95% confidence interval, 0.01-0.08). CONCLUSIONS: In our study, Pseudomonas and Fusarium species are the most common causes of bacterial and fungal keratitis, respectively. Fungal keratitis was more likely than bacterial keratitis to be associated with ocular trauma, whereas fungal keratitis was less likely to be associated with contact lens wear.

Original languageEnglish (US)
Pages (from-to)283-287
Number of pages5
JournalCornea
Volume27
Issue number3
DOIs
StatePublished - Apr 2008
Externally publishedYes

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Corneal Ulcer
Keratitis
Causality
Contact Lenses
Fusarium
Pseudomonas
Acanthamoeba Keratitis
Odds Ratio
Demography
Confidence Intervals
Wounds and Injuries
Thailand
Medical Records
Fungi
Referral and Consultation
Bacteria

Keywords

  • Etiology
  • Predisposing factors
  • Ulcerative keratitis

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Sirikul, T., Prabriputaloong, T., Smathivat, A., Chuck, R. S., & Vongthongsri, A. (2008). Predisposing factors and etiologic diagnosis of ulcerative keratitis. Cornea, 27(3), 283-287. https://doi.org/10.1097/ICO.0b013e31815ca0bb

Predisposing factors and etiologic diagnosis of ulcerative keratitis. / Sirikul, Tasanee; Prabriputaloong, Tisha; Smathivat, Achavee; Chuck, Roy S.; Vongthongsri, Anun.

In: Cornea, Vol. 27, No. 3, 04.2008, p. 283-287.

Research output: Contribution to journalArticle

Sirikul, T, Prabriputaloong, T, Smathivat, A, Chuck, RS & Vongthongsri, A 2008, 'Predisposing factors and etiologic diagnosis of ulcerative keratitis', Cornea, vol. 27, no. 3, pp. 283-287. https://doi.org/10.1097/ICO.0b013e31815ca0bb
Sirikul T, Prabriputaloong T, Smathivat A, Chuck RS, Vongthongsri A. Predisposing factors and etiologic diagnosis of ulcerative keratitis. Cornea. 2008 Apr;27(3):283-287. https://doi.org/10.1097/ICO.0b013e31815ca0bb
Sirikul, Tasanee ; Prabriputaloong, Tisha ; Smathivat, Achavee ; Chuck, Roy S. ; Vongthongsri, Anun. / Predisposing factors and etiologic diagnosis of ulcerative keratitis. In: Cornea. 2008 ; Vol. 27, No. 3. pp. 283-287.
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