Posttranslational modifications of Tubulin

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Abstract

Recent studies have highlighted the potential importance of posttranslational modifications of tubulin in dictating response to antitumor drugs and disease progression. These modifications include glutamylation, glycylation, phosphorylation, acetylation, and tyrosination. Some of the tubulin-modifying enzymes have been identified but the functional consequences of the posttranslational modifications remain largely unknown. In this chapter, we review the posttranslational modifications of tubulin and current knowledge of the role these alterations may play in human disease.

Original languageEnglish (US)
Title of host publicationCytoskeleton and Human Disease
PublisherHumana Press Inc.
Pages241-257
Number of pages17
ISBN (Print)9781617797880, 1617797871, 9781617797873
DOIs
StatePublished - Dec 1 2011

Fingerprint

Post Translational Protein Processing
Tubulin
Acetylation
Phosphorylation
Antineoplastic Agents
Disease Progression
Enzymes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Chao, S. K., Yang, C-P. H., & Band Horwitz, S. (2011). Posttranslational modifications of Tubulin. In Cytoskeleton and Human Disease (pp. 241-257). Humana Press Inc.. https://doi.org/10.1007/978-1-61779-788-0_13

Posttranslational modifications of Tubulin. / Chao, Suzan K.; Yang, Chia-Ping H.; Band Horwitz, Susan.

Cytoskeleton and Human Disease. Humana Press Inc., 2011. p. 241-257.

Research output: Chapter in Book/Report/Conference proceedingChapter

Chao, SK, Yang, C-PH & Band Horwitz, S 2011, Posttranslational modifications of Tubulin. in Cytoskeleton and Human Disease. Humana Press Inc., pp. 241-257. https://doi.org/10.1007/978-1-61779-788-0_13
Chao SK, Yang C-PH, Band Horwitz S. Posttranslational modifications of Tubulin. In Cytoskeleton and Human Disease. Humana Press Inc. 2011. p. 241-257 https://doi.org/10.1007/978-1-61779-788-0_13
Chao, Suzan K. ; Yang, Chia-Ping H. ; Band Horwitz, Susan. / Posttranslational modifications of Tubulin. Cytoskeleton and Human Disease. Humana Press Inc., 2011. pp. 241-257
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