Postoperative radiation therapy for small, low-/intermediate-grade parotid tumors with close and/or positive surgical margins

Samuel M. Richter, Patricia Friedmann, Waleed F. Mourad, Kenneth S. Hu, Mark S. Persky, Louis B. Harrison

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Background. Patients with small, low-/intermediate-risk parotid cancers, treated with surgery, and who have the single prognostic factor of close and/or positive margins, constitute an unusual subset. This study evaluates local control and morbidity associated with postoperative radiation therapy for low/intermediate grade parotid cancer in these patients. Methods. Between 1999 and 2006, 17 patients underwent postoperative radiation therapy at Beth Israel Medical Center for acinic cell carcinoma or low-intermediate-grade mucoepidermoid carcinoma of the parotid with close/positive margins. Pathology, treatment, and follow-up data were retrospectively analyzed for morbidity and local control. Two- and 5-year estimates of survival outcomes were performed followed by an analysis of complications. Results. There were no local failures and no significant long-term complications. Conclusions. Patients with small, low-risk cancer of the parotid gland have excellent local control and low treatment-related morbidity when receiving postoperative radiation therapy for positive or close margins of resection.

Original languageEnglish (US)
Pages (from-to)953-955
Number of pages3
JournalHead and Neck
Volume34
Issue number7
DOIs
StatePublished - Jul 2012
Externally publishedYes

Fingerprint

Parotid Neoplasms
Radiotherapy
Morbidity
Neoplasms
Acinar Cell Carcinoma
Mucoepidermoid Carcinoma
Parotid Gland
Israel
Pathology
Survival
Margins of Excision
Therapeutics

Keywords

  • Low/intermediate grade
  • Parotid tumors
  • Positive/close margins
  • Radiation therapy
  • Surgery

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Postoperative radiation therapy for small, low-/intermediate-grade parotid tumors with close and/or positive surgical margins. / Richter, Samuel M.; Friedmann, Patricia; Mourad, Waleed F.; Hu, Kenneth S.; Persky, Mark S.; Harrison, Louis B.

In: Head and Neck, Vol. 34, No. 7, 07.2012, p. 953-955.

Research output: Contribution to journalArticle

Richter, Samuel M. ; Friedmann, Patricia ; Mourad, Waleed F. ; Hu, Kenneth S. ; Persky, Mark S. ; Harrison, Louis B. / Postoperative radiation therapy for small, low-/intermediate-grade parotid tumors with close and/or positive surgical margins. In: Head and Neck. 2012 ; Vol. 34, No. 7. pp. 953-955.
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AU - Hu, Kenneth S.

AU - Persky, Mark S.

AU - Harrison, Louis B.

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