Posterior reversible encephalopathy syndrome and cerebral sinus thrombosis in a case of pediatric B-Cell ALL

Ellen Fraint, Robin Miller, Andrew Walter

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Posterior reversible encephalopathy syndrome (PRES) and cerebral sinus thrombosis are 2 known complications of acute lymphoblastic leukemia and its treatment. We describe a patient with acute lymphoblastic leukemia whose course was complicated by both of these conditions. This case is novel both for the fact that PRES developed before the initiation of therapy and that PRES was followed shortly by the development of cerebral sinus thrombosis. Our patient's story raises questions about our current understanding of the pathophysiology of PRES, and it suggests that PRES may actually be a predisposing risk factor for cerebral sinus thrombosis.

Original languageEnglish (US)
Pages (from-to)e71-e73
JournalJournal of Pediatric Hematology/Oncology
Volume39
Issue number2
DOIs
StatePublished - 2017
Externally publishedYes

Keywords

  • ALL
  • cerebral sinus thrombosis
  • PRES
  • risk

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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