Post-infarct ventricular septal rupture: early Impella implantation to delay surgery and reduce surgical risk

Marco Bruno Ancona; Damiano Regazzoli; Antonio Mangieri; Fabrizio Monaco; Michele De Bonis; Azeem Latib

doi:10.1007/s12928-016-0428-7

Post-infarct ventricular septal rupture: early Impella implantation to delay surgery and reduce surgical risk

Marco Bruno Ancona, Damiano Regazzoli, Antonio Mangieri, Fabrizio Monaco, Michele De Bonis, Azeem Latib

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Ventricular septal rupture (VSR) is a complication of myocardial infarction. Surgery is the only treatment; however, mortality is high, especially if it is performed within 7 days from presentation. The improved outcome with delayed intervention could be related to evolution of the infarct, which allows a more effective surgical repair. However, it is also a representation of survival bias, as an early surgery is usually performed on individuals with hemodynamic instability. We present a case of VSR complicated by cardiogenic shock. An early hemodynamic stabilization was achieved with Impella implantation; the delay in surgery allowed a reduction in surgical risk.

Original language	English (US)
Pages (from-to)	381-385
Number of pages	5
Journal	Cardiovascular Intervention and Therapeutics
Volume	32
Issue number	4
DOIs	https://doi.org/10.1007/s12928-016-0428-7
State	Published - Oct 1 2017
Externally published	Yes

Keywords

Left ventricular assistance device
Surgical repair
Ventricular septal rupture

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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10.1007/s12928-016-0428-7

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title = "Post-infarct ventricular septal rupture: early Impella implantation to delay surgery and reduce surgical risk",

abstract = "Ventricular septal rupture (VSR) is a complication of myocardial infarction. Surgery is the only treatment; however, mortality is high, especially if it is performed within 7 days from presentation. The improved outcome with delayed intervention could be related to evolution of the infarct, which allows a more effective surgical repair. However, it is also a representation of survival bias, as an early surgery is usually performed on individuals with hemodynamic instability. We present a case of VSR complicated by cardiogenic shock. An early hemodynamic stabilization was achieved with Impella implantation; the delay in surgery allowed a reduction in surgical risk.",

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T1 - Post-infarct ventricular septal rupture

T2 - early Impella implantation to delay surgery and reduce surgical risk

AU - Ancona, Marco Bruno

AU - Regazzoli, Damiano

AU - Mangieri, Antonio

AU - Monaco, Fabrizio

AU - De Bonis, Michele

AU - Latib, Azeem

PY - 2017/10/1

Y1 - 2017/10/1

N2 - Ventricular septal rupture (VSR) is a complication of myocardial infarction. Surgery is the only treatment; however, mortality is high, especially if it is performed within 7 days from presentation. The improved outcome with delayed intervention could be related to evolution of the infarct, which allows a more effective surgical repair. However, it is also a representation of survival bias, as an early surgery is usually performed on individuals with hemodynamic instability. We present a case of VSR complicated by cardiogenic shock. An early hemodynamic stabilization was achieved with Impella implantation; the delay in surgery allowed a reduction in surgical risk.

AB - Ventricular septal rupture (VSR) is a complication of myocardial infarction. Surgery is the only treatment; however, mortality is high, especially if it is performed within 7 days from presentation. The improved outcome with delayed intervention could be related to evolution of the infarct, which allows a more effective surgical repair. However, it is also a representation of survival bias, as an early surgery is usually performed on individuals with hemodynamic instability. We present a case of VSR complicated by cardiogenic shock. An early hemodynamic stabilization was achieved with Impella implantation; the delay in surgery allowed a reduction in surgical risk.

KW - Left ventricular assistance device

KW - Surgical repair

KW - Ventricular septal rupture

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Post-infarct ventricular septal rupture: early Impella implantation to delay surgery and reduce surgical risk

Abstract

Keywords

ASJC Scopus subject areas

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