Possible nonspecific immunopotentiation by 2,4-dinitrochlorobenzene sensitization in patients with hodgkin’s disease

Arye Rubinstein, Nemetallah A. Ghossein, Julian Melamed, J. L. Bosworth, Rae Ann Murphy

Research output: Contribution to journalArticle

Abstract

Various immunological parameters were evaluated in untreated Hodgkin’s patients before and after sensitization with dinitrochlorobenzene (DNCB). The ratio (r) of these parameters after/before DNCB sensitization for patients and second/first samples in the controls were calculated. There were significantly more patients in the r >1.1 group for PH A and Con A responses and for peripheral blood T cell percentages. These data suggest that DNCB sensitization may have a nonspecific immunopotentiation effect.

Original languageEnglish (US)
Pages (from-to)23-26
Number of pages4
JournalONCOLOGY (United States)
Volume36
Issue number1
DOIs
StatePublished - 1979

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Dinitrochlorobenzene
Hodgkin Disease
Blood Cells
T-Lymphocytes

Keywords

  • Dinitrochlorobenzene
  • Hodgkin’s disease
  • Immunopotentiation
  • Sensitization

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Possible nonspecific immunopotentiation by 2,4-dinitrochlorobenzene sensitization in patients with hodgkin’s disease. / Rubinstein, Arye; Ghossein, Nemetallah A.; Melamed, Julian; Bosworth, J. L.; Murphy, Rae Ann.

In: ONCOLOGY (United States), Vol. 36, No. 1, 1979, p. 23-26.

Research output: Contribution to journalArticle

Rubinstein, Arye ; Ghossein, Nemetallah A. ; Melamed, Julian ; Bosworth, J. L. ; Murphy, Rae Ann. / Possible nonspecific immunopotentiation by 2,4-dinitrochlorobenzene sensitization in patients with hodgkin’s disease. In: ONCOLOGY (United States). 1979 ; Vol. 36, No. 1. pp. 23-26.
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