Possible nonspecific immunopotentiation by 2,4-dinitrochlorobenzene sensitization in patients with hodgkin’s disease

Arye Rubinstein, Nemetallah A. Ghossein, Julian Melamed, J. L. Bosworth, Rae Ann Murphy

Research output: Contribution to journalArticle


Various immunological parameters were evaluated in untreated Hodgkin’s patients before and after sensitization with dinitrochlorobenzene (DNCB). The ratio (r) of these parameters after/before DNCB sensitization for patients and second/first samples in the controls were calculated. There were significantly more patients in the r >1.1 group for PH A and Con A responses and for peripheral blood T cell percentages. These data suggest that DNCB sensitization may have a nonspecific immunopotentiation effect.

Original languageEnglish (US)
Pages (from-to)23-26
Number of pages4
JournalOncology (Switzerland)
Issue number1
StatePublished - Jan 1 1979



  • Dinitrochlorobenzene
  • Hodgkin’s disease
  • Immunopotentiation
  • Sensitization

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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