Possible effect of maternal promethazine therapy on neonatal immunologic functions

Arye Rubinstein, Arthur I. Eidelman, Julian Melamed, Lawrence M. Gartner, Stephen Kandall, Harold Schulman

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Abstract

The effect of the administration of promethazine in the treatment of erythroblastosis fetalis was studied in four maternal-fetal pairs. The three infants exposed for a prolonged period of time had decreased neonatal number and function of T cells, and abnormal specific humoral immune responses. The possible role of promethazine in the induction of fetal immunoincompetence is discussed.

Original languageEnglish (US)
Pages (from-to)136-138
Number of pages3
JournalThe Journal of Pediatrics
Volume89
Issue number1
DOIs
Publication statusPublished - Jul 1976

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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