Population epigenetics

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations

Abstract

The field of epigenetics is maturing, with increased interest in understanding the normal regulation of the genome and the possibility that it becomes reprogrammed aberrantly as part of the cause of disease phenotypes. Applying the current technologies and insights to the study of human populations is potentially a way of understanding mechanisms and consequences of these diseases. When extended to encompass health care disparities, understanding why certain populations are unusually prone to specific conditions, there is certainly some potential for gaining new and valuable insights, but these studies are likely to be unusually prone to the effects of confounding influences and need to be designed, executed and interpreted with extra care.

Original languageEnglish (US)
Pages (from-to)84-89
Number of pages6
JournalCurrent Opinion in Systems Biology
Volume1
DOIs
StatePublished - Feb 2017

Keywords

  • DNA methylation
  • Diversity
  • Epigenetics
  • Population
  • Transcription factor

ASJC Scopus subject areas

  • Modeling and Simulation
  • Biochemistry, Genetics and Molecular Biology(all)
  • Drug Discovery
  • Computer Science Applications
  • Applied Mathematics

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