@article{a994176a0c1849c49e0f854028ffc3fe,
title = "Population-based prevalence and incidence estimates of primary discoid lupus erythematosus from the Manhattan Lupus Surveillance Program",
abstract = "Objective Epidemiological data for primary discoid lupus erythematosus (pDLE) remain limited, particularly for racial/ethnic populations in the USA. The Manhattan Lupus Surveillance Program (MLSP) is a population-based retrospective registry of cases with SLE and related diseases including pDLE in Manhattan and was used to provide estimates of the prevalence and incidence of pDLE across major racial/ethnic populations. Methods MLSP cases were identified from rheumatologists, hospitals and population databases. Two case definitions were used for pDLE: the primary case definition which was any physician diagnosis found in the chart and a secondary case definition which was limited to cases diagnosed by a rheumatologist and/or dermatologist. Rates among Manhattan residents were age-adjusted, and capture-recapture analyses were conducted to assess case under-ascertainment. Results Based on the primary definition, age-adjusted overall prevalence and incidence rates of pDLE among Manhattan residents were 6.5 and 0.8 per 100 000 person-years, which increased to 9.0 and 1.3 after capture-recapture adjustment. Prevalence and incidence rates were approximately two and six times higher, respectively, among women compared with men (p<0.0001). Higher prevalence was also found among non-Latino blacks (23.5) and Latinos (8.2) compared with non-Latino whites (1.8) and non-Latino Asians (0.6) (p<0.0001). Incidence was highest among non-Latino blacks (2.4) compared with all other racial/ethnic groups. Similar relationships were observed for the secondary case definition. Conclusion Data from the MLSP provide epidemiological estimates for pDLE among the major racial/ethnic populations in the USA and reveal disparities in pDLE prevalence and incidence by sex and race/ethnicity among Manhattan residents.",
keywords = "Discoid Lupus Erythematosus, Registry, epidemiology",
author = "Peter Izmirly and Jill Buyon and Belmont, {H. Michael} and Sara Sahl and Isabella Wan and Jane Salmon and Anca Askanase and Bathon, {Joan M.} and Laura Geraldino-Pardilla and Yusaf Ali and Ellen Ginzler and Chaim Putterman and Caroline Gordon and Charles Helmick and Hilary Parton",
note = "Funding Information: This work was supported by co-operative agreements between the Centers for Disease Control and Prevention and The New York City Department of Health and Mental Hygiene (grant no. U58/DP002827) and a co-operative agreement between the New York City Department of Health and Mental Hygiene and New York University School of Medicine. Funding Information: Acknowledgements The authors would like to acknowledge Benjamin Wainwright for assistance in preparing the manuscript. The authors wish to thank all of the rheumatologists and their practice managers who participated in the MLSP. We would also like to thank all the administrators in the medical records departments of the hospitals who participated in the MLSP for their assistance obtaining medical records. At the DOHMH, the MLSP would like to acknowledge the contributions of past and current members including Tamira Collins-Bowers, Manasi Joshi, Bonnie Kerker, Maushumi Mavinkurve, Angela Merges, Kyyon Nelson, Viren Shah, Joseph Slade, Lorna Thorpe, Talytha Utley and Elizabeth Waddell. In addition, the MLSP would like to acknowledge the hard work of their abstractors Drs Janice McFarlane, Nick Stefanopoulos, Zahira Zahid, Rukayatu Ibrahim, Saleh Massasati and Simone Shrestha. Contributors Study conception and design: PI, CG, CH, HP. Acquisition of data: PI, JB, IW, HMB, SS, JS, AA, JMB, LG-P, YA, EG, CP, HP. Analysis and interpretation of data: PI, JB, CH, HP. Funding This work was supported by co-operative agreements between the Centers for Disease Control and Prevention and The New York City Department of Health and Mental Hygiene (grant no. U58/DP002827) and a co-operative agreement between the New York City Department of Health and Mental Hygiene and New York University School of Medicine. Publisher Copyright: {\textcopyright} {\textcopyright} Author(s) (or their employer(s)) 2019.",
year = "2019",
month = oct,
day = "1",
doi = "10.1136/lupus-2019-000344",
language = "English (US)",
volume = "6",
journal = "Lupus Science and Medicine",
issn = "2053-8790",
publisher = "BMJ Publishing Group",
number = "1",
}