Point dose variations with time during traditional brachytherapy for cervical carcinoma

Gwendolyn C. King, William D. Bloomer, Shalom Kalnicki, Clare M. Faul, William E. Gooding, Todd F. Stockstill, Andrew Wu, Roy Buchsbaum, Alex S. Chen, Kristina Gerszten, Andre Kalend

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

In traditional brachytherapy for carcinoma of the cervix, doses are often prescribed to specifically chosen points (A and B) and the normal tissue tolerance calculated at specific reference points in the bladder and rectum. These tolerance doses are often used to modify the brachytherapy treatment plan. It is inherently assumed that the position of the brachytherapy applicator does not change in relation to the relevant anatomical structures over the time-course of an implant. To assess the accuracy of this assumption, 2 sets of localization films were obtained for each implant in 28 patients, 1 prior to loading and another after the removal of the radioactive sources. Significant applicator movement and, consequently, significant dose variations were observed. Therefore, isolated one-time dose measurements to normal critical structures should not be used as the sole basis for making therapeutic decisions. The magnitude of dose variations and their clinical significant are discussed. (C) 2000 American Association of Medical Dosimetrists.

Original languageEnglish (US)
Pages (from-to)77-80
Number of pages4
JournalMedical Dosimetry
Volume25
Issue number2
DOIs
StatePublished - Mar 2000
Externally publishedYes

Fingerprint

Brachytherapy
cancer
Carcinoma
dosage
Rectum
Cervix Uteri
Decision Making
Urinary Bladder
rectum
bladder
Therapeutics

Keywords

  • Bladder
  • Brachytherapy
  • Carcinoma of uterus
  • Cervix
  • Dosimetry
  • Rectum

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Health Professions(all)
  • Radiation

Cite this

King, G. C., Bloomer, W. D., Kalnicki, S., Faul, C. M., Gooding, W. E., Stockstill, T. F., ... Kalend, A. (2000). Point dose variations with time during traditional brachytherapy for cervical carcinoma. Medical Dosimetry, 25(2), 77-80. https://doi.org/10.1016/S0958-3947(00)00032-7

Point dose variations with time during traditional brachytherapy for cervical carcinoma. / King, Gwendolyn C.; Bloomer, William D.; Kalnicki, Shalom; Faul, Clare M.; Gooding, William E.; Stockstill, Todd F.; Wu, Andrew; Buchsbaum, Roy; Chen, Alex S.; Gerszten, Kristina; Kalend, Andre.

In: Medical Dosimetry, Vol. 25, No. 2, 03.2000, p. 77-80.

Research output: Contribution to journalArticle

King, GC, Bloomer, WD, Kalnicki, S, Faul, CM, Gooding, WE, Stockstill, TF, Wu, A, Buchsbaum, R, Chen, AS, Gerszten, K & Kalend, A 2000, 'Point dose variations with time during traditional brachytherapy for cervical carcinoma', Medical Dosimetry, vol. 25, no. 2, pp. 77-80. https://doi.org/10.1016/S0958-3947(00)00032-7
King, Gwendolyn C. ; Bloomer, William D. ; Kalnicki, Shalom ; Faul, Clare M. ; Gooding, William E. ; Stockstill, Todd F. ; Wu, Andrew ; Buchsbaum, Roy ; Chen, Alex S. ; Gerszten, Kristina ; Kalend, Andre. / Point dose variations with time during traditional brachytherapy for cervical carcinoma. In: Medical Dosimetry. 2000 ; Vol. 25, No. 2. pp. 77-80.
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