Platinum-based combination chemotherapy for the treatment of advanced-stage squamous cell carcinoma of the vulva.

Jimmy Belotte, Awoniyi O. Awonuga, Rashmi Bolinjkar, Mitchell Alexis, Farah Tabassum, Gunter Deppe

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Chemoradiation is an alternative to radical vulvectomy with en bloc node dissection for advanced vulvar cancer. We report a case of complete clinical and pathologic response with chemotherapy alone in a patient with advanced vulvar cancer. A middle-aged woman known to have had human immunodeficiency virus (HIV) for 10 years was newly diagnosed with advanced-stage squamous carcinoma of the vulva. She was treated with a total of nine cycles of platinum-based combination chemotherapy, with complete clinical and pathologic response. She remains in complete clinical remission without evidence of recurrent disease by noninvasive testing in the absence of any further therapy 24 months after her last chemotherapy treatment. Platinum-based combination chemotherapy may be used successfully for patients with advanced-stage squamous carcinoma of the vulva.

Original languageEnglish (US)
Pages (from-to)458-460
Number of pages3
JournalObstetrics and Gynecology
Volume120
Issue number2 Pt 2
StatePublished - Aug 1 2012
Externally publishedYes

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Vulvar Neoplasms
Vulva
Combination Drug Therapy
Platinum
Squamous Cell Carcinoma
Drug Therapy
Dissection
HIV
Therapeutics

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Belotte, J., Awonuga, A. O., Bolinjkar, R., Alexis, M., Tabassum, F., & Deppe, G. (2012). Platinum-based combination chemotherapy for the treatment of advanced-stage squamous cell carcinoma of the vulva. Obstetrics and Gynecology, 120(2 Pt 2), 458-460.

Platinum-based combination chemotherapy for the treatment of advanced-stage squamous cell carcinoma of the vulva. / Belotte, Jimmy; Awonuga, Awoniyi O.; Bolinjkar, Rashmi; Alexis, Mitchell; Tabassum, Farah; Deppe, Gunter.

In: Obstetrics and Gynecology, Vol. 120, No. 2 Pt 2, 01.08.2012, p. 458-460.

Research output: Contribution to journalArticle

Belotte, J, Awonuga, AO, Bolinjkar, R, Alexis, M, Tabassum, F & Deppe, G 2012, 'Platinum-based combination chemotherapy for the treatment of advanced-stage squamous cell carcinoma of the vulva.', Obstetrics and Gynecology, vol. 120, no. 2 Pt 2, pp. 458-460.
Belotte, Jimmy ; Awonuga, Awoniyi O. ; Bolinjkar, Rashmi ; Alexis, Mitchell ; Tabassum, Farah ; Deppe, Gunter. / Platinum-based combination chemotherapy for the treatment of advanced-stage squamous cell carcinoma of the vulva. In: Obstetrics and Gynecology. 2012 ; Vol. 120, No. 2 Pt 2. pp. 458-460.
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