Abstract
Plasma concentrations of oxytocin and vasopressin were determined by radioimmunoassay in a woman with clinical diabetes insipidus. Plasma oxytocin levels were normal and ranged from less than 0.25 µU/ml to 76 µU/ml during the last month of pregnancy and during spontaneous labor. Vasopressin requirements did not change during pregnancy. Unexplained vasopressin resistance and massive diuresis occurred early in the postpartum period. Plasma vasopressin concentrations were undetectable in the nonpregnant state. The documentation of normal oxytocin production and total vasopressin deficiency suggests that an anatomic defect is unlikely to cause this disorder unless it is limited to axons and cell bodies containing vasopressin and not oxytocin.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 662-667 |
| Number of pages | 6 |
| Journal | Obstetrics and Gynecology |
| Volume | 61 |
| Issue number | 5 |
| State | Published - 1983 |
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ASJC Scopus subject areas
- Obstetrics and Gynecology
Cite this
Plasma oxytocin concentrations in a pregnant woman with total vasopressin deficiency. / Shangold, Mona M.; Freeman, Ruth; Kumaresan, P.; Feder, Arlene S.; Vasicka, Alois.
In: Obstetrics and Gynecology, Vol. 61, No. 5, 1983, p. 662-667.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Plasma oxytocin concentrations in a pregnant woman with total vasopressin deficiency
AU - Shangold, Mona M.
AU - Freeman, Ruth
AU - Kumaresan, P.
AU - Feder, Arlene S.
AU - Vasicka, Alois
PY - 1983
Y1 - 1983
N2 - Plasma concentrations of oxytocin and vasopressin were determined by radioimmunoassay in a woman with clinical diabetes insipidus. Plasma oxytocin levels were normal and ranged from less than 0.25 µU/ml to 76 µU/ml during the last month of pregnancy and during spontaneous labor. Vasopressin requirements did not change during pregnancy. Unexplained vasopressin resistance and massive diuresis occurred early in the postpartum period. Plasma vasopressin concentrations were undetectable in the nonpregnant state. The documentation of normal oxytocin production and total vasopressin deficiency suggests that an anatomic defect is unlikely to cause this disorder unless it is limited to axons and cell bodies containing vasopressin and not oxytocin.
AB - Plasma concentrations of oxytocin and vasopressin were determined by radioimmunoassay in a woman with clinical diabetes insipidus. Plasma oxytocin levels were normal and ranged from less than 0.25 µU/ml to 76 µU/ml during the last month of pregnancy and during spontaneous labor. Vasopressin requirements did not change during pregnancy. Unexplained vasopressin resistance and massive diuresis occurred early in the postpartum period. Plasma vasopressin concentrations were undetectable in the nonpregnant state. The documentation of normal oxytocin production and total vasopressin deficiency suggests that an anatomic defect is unlikely to cause this disorder unless it is limited to axons and cell bodies containing vasopressin and not oxytocin.
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UR - http://www.scopus.com/inward/citedby.url?scp=0020625448&partnerID=8YFLogxK
M3 - Article
VL - 61
SP - 662
EP - 667
JO - Obstetrics and Gynecology
JF - Obstetrics and Gynecology
SN - 0029-7844
IS - 5
ER -