Plasma glucose and tumour necrosis factor-α in adult patients with severe falciparum malaria

R. Manish, R. Tripathy, B. K. Das

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

Plasma glucose was assessed in 81 patients with severe falciparum malaria at the time of presentation along with tumour necrosis factor-α (TNF-α). The lowest plasma glucose value was 3.38 mmol/l and none of the patients had hypoglycaemia at admission. Plasma glucose values were not significantly lower in those with multiple organ dysfunction (MOD) than in patients with single organ dysfunction (cerebral malaria only) and in those who died compared with patients who survived. Conversely, TNF-α showed a good correlation with depth of coma and was significantly higher in patients who had MOD and those who died. There was no correlation between plasma glucose and TNF-α values.

Original languageEnglish (US)
Pages (from-to)125-128
Number of pages4
JournalTropical Medicine and International Health
Volume8
Issue number2
DOIs
StatePublished - Feb 1 2003
Externally publishedYes

Keywords

  • Adults
  • Plasma glucose
  • Severe falciparum malaria
  • Tumour necrosis factor-α

ASJC Scopus subject areas

  • Parasitology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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