Placebo-controlled study of oral terbutaline and pseudoephedrine in management of prostaglandin E1-induced prolonged erections

Franklin C. Lowe, Jonathan P. Jarow

Research output: Contribution to journalArticle

73 Scopus citations


Prolonged erections, priapism, secondary to pharmacologic stimulation are usually treated by drainage of the corporeal bodies and irrigation with a sympathomimetic. To study the efficacy of oral medical therapy in the treatment of priapism, 75 patients with pharmacologically induced (prostaglandin E 1) prolonged erections were randomized to receive terbutaline, pseudoephedrine, or placebo. Detumescence occurred in 36 percent, 28 percent, and 12 percent, respectively. Terbutaline was significantly better than placebo (p < 0.05) in achieving detumescence. The results of this study suggest that oral terbutaline should be considered in the initial management of pharmacologically induced prolonged erections.

Original languageEnglish (US)
Pages (from-to)51-53
Number of pages3
Issue number1
StatePublished - Jul 1993
Externally publishedYes


ASJC Scopus subject areas

  • Urology

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